A dietary carbohydrate – gut Parasutterella – human fatty acid biosynthesis metabolic axis in obesity and type 2 diabetes

L Henneke, K Schlicht, NA Andreani, T Hollstein… - Gut …, 2022 - Taylor & Francis
Recent rodent microbiome experiments suggest that besides Akkermansia, Parasutterella
sp. are important in type 2 diabetes and obesity development. In the present translational …

A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility

M Wei, F Huang, L Zhao, Y Zhang, W Yang, S Wang… - …, 2020 - thelancet.com
Background The composition of the bile acid (BA) pool is closely associated with obesity
and is modified by gut microbiota. Perturbations of gut microbiota shape the BA composition …

Gut microbiota induces DNA methylation via SCFAs predisposing obesity-prone individuals to diabetes

W Guo, Z Zhang, L Li, X Liang, Y Wu, X Wang… - Pharmacological …, 2022 - Elsevier
Obesity-prone (OP) individuals have a significant predisposition to obesity and diabetes.
Previously, we have found that OP individuals, despite being normal in weight and BMI …

Gut Microbiota and Obesity: The Chicken or the Egg?

DS Tassoni, RCO Macedo, FM Delpino, HO Santos - Obesities, 2023 - mdpi.com
Although the link between gut microbiota and obesity is increasingly reported, the
pathophysiological mechanisms and clinical outcomes are still under debate. This overview …

Correlations between α-linolenic acid-improved multitissue homeostasis and gut microbiota in mice fed a high-fat diet

X Gao, S Chang, S Liu, L Peng, J Xie, W Dong, Y Tian… - Msystems, 2020 - Am Soc Microbiol
Previous studies have shown that α-linolenic acid (ALA) has a significant regulatory effect on
related disorders induced by high-fat diets (HFDs), but little is known regarding the …

Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome

RM Golonka, M Vijay-Kumar - Advances in cancer research, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide. Much recent research has delved into understanding the underlying molecular …

Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis

Y Pang, Y Zheng, N Yang, M Zan, L Zhang… - Lipids in Health and …, 2022 - Springer
Background Although obesity is caused by different factors, individual susceptibility to
obesity differs among people under the same circumstances. The microbiota in the caecum …

Uridine attenuates obesity, ameliorates hepatic lipid accumulation and modifies the gut microbiota composition in mice fed with a high-fat diet

Y Liu, C Xie, Z Zhai, Z Deng, HR De Jonge, X Wu… - Food & Function, 2021 - pubs.rsc.org
Uridine (UR) is a pyrimidine nucleoside that plays an important role in regulating glucose
and lipid metabolism. The aim of this study was to investigate the effect of UR on obesity, fat …

Gut microbiota differentially mediated by Qingmao tea and Qingzhuan tea alleviated high-fat-induced obesity and associated metabolic disorders: The impact of …

L Cheng, Y Wei, L Xu, L Peng, Y Wang, X Wei - Foods, 2022 - mdpi.com
Although dark tea is a unique microbial-fermented tea with a high reputation for having an
antiobesity effect, little is known about the effect of microbial fermentation on tea leaves' …

Fecal microbiome alteration may be a potential marker for gastric cancer

J Wu, C Zhang, S Xu, C Xiang, R Wang… - Disease …, 2020 - Wiley Online Library
Although intestinal microbial dysbiosis was confirmed to be associated with many chronic
diseases and health status through complicated interaction with the host, the effect on …