Animals and humans are exposed each day to a multitude of chemicals in the air, water and
food. They have developed a battery of enzymes and transporters that facilitate the …

Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH)
superfamily of transcription factors, which are associated with cellular responses to …

Arthropods have well adapted to the vast array of chemicals they encounter in their
environment. Whether these xenobiotics are plant allelochemicals or anthropogenic …

Monitoring of chemicals in the aquatic environment by chemical analysis alone cannot
completely assess and predict the effects of chemicals on aquatic species and ecosystems …

The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor and transcription factor
activated through cognate ligand binding. It is an important factor in immunity and tissue …

Ecological risk assessors face increasing demands to assess more chemicals, with greater
speed and accuracy, and to do so using fewer resources and experimental animals. New …

The aryl hydrocarbon receptor (AhR) is a transcriptional factor that regulates multiple
functions following its activation by a variety of ligands, including xenobiotics, natural …

Zebrafish (Danio rerio) has been a prominent model vertebrate in a variety of biological
disciplines. Substantial information gathered from developmental and genetic research …

Each year ecotoxicological problems become increasingly complex and encompass
broader spatial and temporal scales. Our practical understanding must evolve accordingly to …

Drug metabolizing enzymes (DMEs) play central roles in the metabolism, elimination and
detoxification of xenobiotics and drugs introduced into the human body. Most of the tissues …