Poly (ADP-ribose) polymerase: a new therapeutic target?

D Gerö, C Szabó - Current Opinion in Anesthesiology, 2008 - journals.lww.com
Poly(ADP-ribose) polymerase: a new therapeutic target? : Current Opinion in
Anesthesiology Poly(ADP-ribose) polymerase: a new therapeutic target? : Current Opinion …

Diabetes‐induced overexpression of endothelin‐1 and endothelin receptors in the rat renal cortex is mediated via poly (ADP‐ribose) polymerase activation

AG Minchenko, MJ Stevens, L White… - The FASEB …, 2003 - Wiley Online Library
We hypothesize that poly (ADP‐ribosyl) ation, that is, poly (ADP‐ribose) polymerase (PARP)‐
dependent transfer of ADP‐ribose moieties from NAD to nuclear proteins, plays a role in …

C‐peptide inhibits leukocyte‐endothelium interaction in the microcirculation during acute endothelial dysfunction

R Scalia, KM Coyle, BJ Levine, G Booth… - The FASEB …, 2000 - Wiley Online Library
C‐peptide is a cleavage product that comes from processing proinsulin to insulin that
induces nitric oxide (NO)‐mediated vasodilation. NO modulates leukocyte‐endothelium …

Hemorrhage-induced vascular hyporeactivity to norepinephrine in select vasculatures of rats and the roles of nitric oxide and endothelin

L Liu, JA Ward, MA Dubick - Shock, 2003 - journals.lww.com
Hemorrhage-induced vascular hyporeactivity to norepinephrine (NE) and the possible
effector roles of nitric oxide (NO) and endothelin (ET) were investigated in different vascular …

Hemorrhagic shock-induced vascular hyporeactivity in the rat: relationship to gene expression of nitric oxide synthase, endothelin-1, and select cytokines in …

L Liu, MA Dubick - Journal of Surgical Research, 2005 - Elsevier
BACKGROUND: Our previous work observed that vascular hyporeactivity to norepinephrine
(NE) developed after hemorrhage and the response was not the same in the 4 arteries …

Hypoxic regulation of EDN1, EDNRA, EDNRB, and ECE1 gene expressions in ERN1 knockdown U87 glioma cells

DO Minchenko, DO Tsymbal, OO Riabovol… - Endocrine …, 2019 - sciendo.com
Objective. The aim of the present investigation was to study the effect of hypoxia on the
expression of genes encoding endothelin-1 (EDN1) and its cognate receptors (EDNRA and …

Inhibitors of poly (ADP-Ribose) polymerase-1 as agents providing correction of brain dysfunctions induced by experimental diabetes

MM Guzyk, KO Dyakun, LV Yanytska, IB Pryvrotska… - Neurophysiology, 2017 - Springer
The effects of 1, 5-isoquinolinediol (IQD) and nicotinamide (NAm), inhibitors of poly-(ADP-
ribose) polymerase-1 (PARP-1), on inflammatory processes and activation of PARP-1 under …

中心静脉穿刺置管术在创伤性休克中的应用

陈保甲, 张帆 - 中国现代医学杂志, 2005 - cqvip.com
目的分析, 探讨中心静脉穿刺置管术在抢救创伤性休克中的应用和效果. 方法2000 年8 月~ 2004
年3 月, 在52 例急诊创伤性休克治疗中, 应用中心静脉穿刺置管术快速, 有效地建立输液通道 …

创伤性休克大鼠血浆内皮素与组织氧分压变化的实验研究

孙英刚, 黄宗海, 厉周, 雷洪伊, 林洪武, 孙高斌 - 解放军医学杂志, 2003 - cqvip.com
观察创伤性休克过程中血浆内皮素与组织氧分压的动态变化, 探讨内皮素在创伤性休克过程中的
意义. 采用后肢创伤法建立创伤性休克大鼠模型, 观察创伤前后血浆内皮素 …

Effects of crystalloid and colloid resuscitation on hemorrhage-induced vascular hyporesponsiveness to norepinephrine in the rat

LM Liu, JA Ward, MA Dubick - Journal of Trauma and Acute Care …, 2003 - journals.lww.com
Background We have shown previously that hemorrhagic hypotension is associated with a
progressive development of vascular hyporeactivity to norepinephrine (NE). The present …