Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

The bioavailability, transport, and bioactivity of dietary flavonoids: A review from a historical perspective

G Williamson, CD Kay, A Crozier - Comprehensive Reviews in …, 2018 - Wiley Online Library
Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …

p38 MAPK signaling in osteoblast differentiation

E Rodríguez-Carballo, B Gámez… - Frontiers in cell and …, 2016 - frontiersin.org
The skeleton is a highly dynamic tissue whose structure relies on the balance between bone
deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast …

[HTML][HTML] Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition

D Rémond, DR Shahar, D Gille, P Pinto, J Kachal… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic
understanding of the impact of aging on the intake, digestion, and absorption of nutrients is …

Therapeutic effects of citrus flavonoids neohesperidin, hesperidin and its aglycone, hesperetin on bone health

AC Ortiz, SOM Fideles, CHB Reis, MZ Bellini… - Biomolecules, 2022 - mdpi.com
Flavonoids are natural phytochemicals that have therapeutic effects and act in the
prevention of several pathologies. These phytochemicals can be found in seeds, grains, tea …

Nutrition and healthy aging: Prevention and treatment of gastrointestinal diseases

NM Cristina, A Lucia - Nutrients, 2021 - mdpi.com
Nutritional well-being is a fundamental aspect for the health, autonomy and, therefore, the
quality of life of all people, but especially of the elderly. It is estimated that at least half of non …

Effects of flavonoids incorporated biological macromolecules based scaffolds in bone tissue engineering

SP Soundarya, V Sanjay, AH Menon, S Dhivya… - International journal of …, 2018 - Elsevier
Skeletal tissue damage caused by trauma, injury, or disease can often result in considerable
morbidity and the need for new, more reliable strategies for skeletal regeneration. So, to …

Molecular signaling mechanisms behind polyphenol-induced bone anabolism

E Torre - Phytochemistry Reviews, 2017 - Springer
For millennia, in the different cultures all over the world, plants have been extensively used
as a source of therapeutic agents with wide-ranging medicinal applications, thus becoming …

Catechins and proanthocyanidins involvement in metabolic syndrome

GT Patanè, S Putaggio, E Tellone, D Barreca… - International Journal of …, 2023 - mdpi.com
Recent studies on natural antioxidant compounds have highlighted their potentiality against
various pathological conditions. The present review aims to selectively evaluate the benefits …

Therapeutic potential of naringenin nanosuspension: in vitro and in vivo anti-osteoporotic studies

S Gera, S Sampathi, S Maddukuri, S Dodoala… - Pharmaceutics, 2022 - mdpi.com
Naringenin (NRG) is a flavonoid and has been reported as an anti-osteoporotic agent.
However, poor bioavailability may limit the anti-osteoporotic potential of the drug. The …