Traumatic brain injury and suicidal behavior: a review

A Wadhawan, JW Stiller, E Potocki… - Journal of …, 2019 - content.iospress.com
Given the increasing rate of death by suicide in the United States, it is imperative to examine
specific risk factors and to identify possible etiologies of suicidal behavior in at-risk clinical …

Relevance of 5-HT2A Receptor Modulation of Pyramidal Cell Excitability for Dementia-Related Psychosis: Implications for Pharmacotherapy

ES Burstein - CNS drugs, 2021 - Springer
Psychosis occurs across a wide variety of dementias with differing etiologies, including
Alzheimer's dementia, Parkinson's dementia, Lewy body dementia, frontotemporal …

From hybrids to new scaffolds: the latest medicinal chemistry goals in multi-target directed ligands for Alzheimer's disease

J Alarcón-Espósito, M Mallea… - Current …, 2021 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic, progressive, and fatal neurodegenerative disorder
affecting cognition, behavior, and function, being one of the most common causes of mental …

5-HT6 receptor memory and amnesia: behavioral pharmacology–learning and memory processes

A Meneses, G Pérez-García, T Ponce-Lopez… - International review of …, 2011 - Elsevier
Growing evidence indicates that antagonists of the 5-hydroxytryptamine (serotonin) receptor
6 (5-HT 6) improve memory and reverse amnesia, although the mechanisms involved are …

Agonist and antagonist bind differently to 5-HT1A receptors during Alzheimer's disease: a post-mortem study with PET radiopharmaceuticals

B Vidal, J Sebti, M Verdurand, S Fieux, T Billard… - …, 2016 - Elsevier
PET imaging studies using 5-HT 1A receptor radiotracers show a decreased density of this
receptor in hippocampi of patients with Alzheimer's disease (AD) at advanced stages …

Memory formation and memory alterations: 5-HT6 and 5-HT7 receptors, novel alternative

A Meneses - Reviews in the Neurosciences, 2014 - degruyter.com
Agonists and antagonists of the 5-hydroxytryptamine (serotonin) receptor6 (5-HT6) or
receptor7 (5-HT7) might improve memory and/or reverse amnesia, although the …

Serotonin 5-HT6 receptor antagonists for the treatment of Alzheimer's disease

WJ Geldenhuys… - Current Topics in Medicinal …, 2008 - ingentaconnect.com
Recently, the serotonin 5-HT6 receptor has been identified as a drug target for attenuating
cognitive deficits associated with Alzheimer's disease (AD). Additionally, this receptor may …

[HTML][HTML] Opportunities for multiscale computational modelling of serotonergic drug effects in Alzheimer's disease

A Joshi, DH Wang, S Watterson, PL McClean… - …, 2020 - Elsevier
Alzheimer's disease (AD) is an age-specific neurodegenerative disease that compromises
cognitive functioning and impacts the quality of life of an individual. Pathologically, AD is …

[HTML][HTML] Neuroprotective effects of 1δ-1-acetoxyeugenol acetate on Aβ (25-35) induced cognitive dysfunction in mice

HSJ Chellammal, A Veerachamy… - Biomedicine & …, 2019 - Elsevier
The progressive accumulation of amyloid beta (Aβ) peptide is neurotoxic and leads to
Alzheimer's type dementia. Accumulation of Aβ has been associated with dysfunction of …

Age-related alterations in the behavior and serotonin-related gene mRNA levels in the brain of males and females of short-lived turquoise killifish (Nothobranchius …

VS Evsiukova, EA Kulikova, AV Kulikov - Biomolecules, 2021 - mdpi.com
Short-lived turquoise killifish (Nothobranchius furzeri) have become a popular model
organism for neuroscience. In the present paper we study for the first time their behavior in …