[HTML][HTML] Metabolomics in hepatocellular carcinoma: From biomarker discovery to precision medicine

X Wu, Z Wang, L Luo, D Shu, K Wang - Frontiers in Medical …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) remains a global health burden, and is mostly diagnosed
at late and advanced stages. Currently, limited and insensitive diagnostic modalities …

c (RGDfK) anchored surface manipulated liposome for tumor-targeted Tyrosine Kinase Inhibitor (TKI) delivery to potentiate liver anticancer activity

P Deepak, P Kumar, DK Arya, P Pandey… - International Journal of …, 2023 - Elsevier
Current anticancer drug research includes tumor-targeted administration as a critical
component because it is the best strategy to boost efficacy and decrease toxicity. Low drug …

[HTML][HTML] Utilizing gut microbiota to improve hepatobiliary tumor treatments: recent advances

H Qin, B Yuan, W Huang, Y Wang - Frontiers in Oncology, 2022 - frontiersin.org
Hepatobiliary tumors, which include cholangiocarcinoma, hepatocellular carcinoma (HCC),
and gallbladder cancer, are common cancers that have high morbidity and mortality rates …

[HTML][HTML] Chronic intermittent hypoxia increases cell proliferation in hepatocellular carcinoma

L Carreres, M Mercey-Ressejac, K Kurma, J Ghelfi… - Cells, 2022 - mdpi.com
Obstructive sleep apnea (OSA) syndrome is characterized by chronic intermittent hypoxia
and is associated with an increased risk of all-cause mortality, including cancer mortality …

Escin‐sorafenib synergy up‐regulates LC3‐II and p62 to induce apoptosis in hepatocellular carcinoma cells

Y Hussain, J Singh, A Meena, RA Sinha… - Environmental …, 2024 - Wiley Online Library
Introduction Hepatocellular carcinoma (HCC) is a common solid cancer and the leading
cause of cancer deaths worldwide. Sorafenib is the first drug used to treat HCC but its …

Escin enhanced the efficacy of sorafenib by autophagy‐mediated apoptosis in lung cancer cells

Y Hussain, J Singh, A Meena, RA Sinha… - Phytotherapy …, 2023 - Wiley Online Library
Combining anti‐cancer drugs has been exploited as promising treatment strategy to target
lung cancer. Synergistic chemotherapies increase anti‐cancer effect and reduce effective …

[HTML][HTML] Pomegranate juice and punicalagin-mediated chemoprevention of hepatocellular carcinogenesis via regulating miR-21 and NF-κB-p65 in a rat model

AM Hussein, NM El-Beih, M Swellam… - Cancer Cell …, 2022 - Springer
Background Hepatocellular carcinoma (HCC) is the most common neoplasm among primary
liver malignancies, accounting for 70%–85% of total liver cancer cases worldwide. It is also …

[HTML][HTML] A Dual Coverage Monitoring of the Bile Acids Profile in the Liver–Gut Axis throughout the Whole Inflammation-Cancer Transformation Progressive: Reveal …

L Xing, Y Zhang, S Li, M Tong, K Bi, Q Zhang… - International Journal of …, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) is the terminal phase of multiple chronic liver diseases,
and evidence supports chronic uncontrollable inflammation being one of the potential …

Preclinical Development and Validation of Translational Temperature Sensitive Iodized Oil Emulsion Mediated Transcatheter Arterial Chemo‐Immuno‐Embolization …

H Kim, B Choi, SK Mouli, H Choi… - Advanced …, 2023 - Wiley Online Library
Herein a practical strategy for augmenting immune activation in transcatheter arterial
chemoembolization (TACE) of hepatocellular carcinoma (HCC) is presented. Pluronic F127 …

[HTML][HTML] Anticancer effect of selenium/chitosan/polyethylene glycol/allyl isothiocyanate nanocomposites against diethylnitrosamine-induced liver cancer in rats

C Li, SH Salmen, TA Alahmadi… - Saudi journal of …, 2022 - Elsevier
Background Nano-based drug delivery systems have shown several advantages in cancer
treatment like specific targeting of cancer cells, good pharmacokinetics, and lesser adverse …