Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Cationic antimicrobial peptides are a class of small, positively charged peptides known for
their broad-spectrum antimicrobial activity. These peptides have also been shown to …

Antimicrobial peptides (AMP) are highly diverse and dynamic molecules that are expressed
by specific intestinal epithelial cells, Paneth cells, as well as immune cells in the …

Defensins comprise one of the largest groups of host defence peptides, present throughout
evolution, in fungi and flowering plants as well as in invertebrates and vertebrates. These …

Mammalian defensins are small, cationic, antimicrobial peptides encoded by the host that
are considered to be important antibiotic-like effectors of innate immunity. By using …

A popular and successful strategy in semi-rational design of protein stability is the use of
evolutionary information encapsulated in homologous protein sequences. Consensus …

Antimicrobial peptides play a crucial role in innate immunity, whose components are mainly
peptide‐based molecules with antibacterial properties. Indeed, the exploration of the …

Antimicrobial peptides (AMPs) are the natural antibiotics recognized for their broad-
spectrum resistance to bacteria, fungi, viruses and parasites, and influencing the host …

The last decade led to the discovery and characterization of several human β-defensins.
Analysis of genomic information indicates that the number of β-defensin-like molecules …

Mammals generate a diverse array of antimicrobial proteins, largely represented by
defensins or cathelicidins. The direct in vitro microbicidal activity of antimicrobial proteins …