New Findings What is the topic of this review? Cerebrovascular reactivity to CO2, which is a
principal factor in determining ventilatory responses to CO2 through the role reactivity plays …

The brain is a vital organ that relies on a constant and adequate supply of blood to match
oxygen and glucose delivery with the local metabolic demands of active neurones. It is well …

New Findings What is the central question of this study? What are the mechanisms
responsible for the decline in cognitive performance following exposure to acute normobaric …

We compared the integrated cardiovascular and autonomic responses to hypercapnia and
hypoxia to test the hypothesis that these stimuli differentially affect muscle sympathetic nerve …

New Findings• What is the central question of this study? Does hypoxia enhance blood flow
to all parts of the brain uniformly?• What is the main finding and its importance? During …

Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in
neurovascular coupling. NO produced by neurons diffuses into the smooth muscle …

Although it has been traditionally thought that decreasing SpO 2 with ascent to high altitudes
not only induces acute mountain sickness but also can decrease executive function, the …

New Findings What is the central question of this study? We aimed to characterize the
cardiorespiratory and cerebrovascular responses to transient and steady‐state tests of the …

New Findings What is the central question of this study? We investigated the interaction
between central and peripheral respiratory chemoreceptors in healthy, awake human …

High altitude (HA) ascent imposes systemic hypoxia and associated risk of acute mountain
sickness. Acute hypoxia elicits a hypoxic ventilatory response (HVR), which is augmented …