[HTML][HTML] Phage Therapy: Targeting Intestinal Bacterial Microbiota for Treatment of Liver Diseases

J Fujiki, B Schnabl - JHEP Reports, 2023 - Elsevier
Phage therapy has been overshadowed by antibiotics for decades. However, it has been
revitalized as a powerful approach against antimicrobial-resistant bacteria. As the bacterial …

[HTML][HTML] Fitness trade-offs between phage and antibiotic sensitivity in phage-resistant variants: molecular action and insights into clinical applications for phage …

J Fujiki, K Nakamura, T Nakamura, H Iwano - International Journal of …, 2023 - mdpi.com
In recent decades, phage therapy has been overshadowed by the widespread use of
antibiotics in Western countries. However, it has been revitalized as a powerful approach …

[HTML][HTML] Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University

S Würstle, A Lee, KE Kortright, F Winzig, W An… - Scientific Reports, 2024 - nature.com
Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent
bacterial infections, and the year 2021 marked the centennial of Felix d'Hérelle's first …

Addressing the research and development gaps in modern phage therapy

PE Turner, J Azeredo, ET Buurman, S Green… - Phage, 2024 - liebertpub.com
Antimicrobial resistance is on the rise globally, prompting increased research and
development (R&D) of phage therapy as a strategy to address difficult-to-treat bacterial …

[HTML][HTML] Current Knowledge and Perspectives of Phage Therapy for Combating Refractory Wound Infections

B Wang, L Du, B Dong, E Kou, L Wang… - International Journal of …, 2024 - mdpi.com
Wound infection is one of the most important factors affecting wound healing, so its effective
control is critical to promote the process of wound healing. However, with the increasing …

Strategies for the construction of multicyclic phage display libraries

FJ Chen, N Pinnette, J Gao - ChemBioChem, 2024 - Wiley Online Library
Peptide therapeutics have gained great interest due to their multiple advantages over small
molecule and antibody‐based drugs. Peptide drugs are easier to synthesize, have the …

[HTML][HTML] Bacteriophage bioengineering: A transformative approach for targeted drug discovery and beyond

L Cui, S Veeranarayanan, K Thitiananpakorn… - Pathogens, 2023 - mdpi.com
Bacteriophages, the viruses that infect and replicate within bacteria, have long been
recognized as potential therapeutic agents against bacterial infections. The rise of antibiotic …

Phage-Based antibacterial hydrogels for bacterial targeting and Ablation: Progress and perspective

H Bai, Q Borjihan, Z Li, P Qin, J Cheng, D Xiao… - European Journal of …, 2024 - Elsevier
The emergence of drug-resistant bacteria makes antibiotics inadequate to treat bacterial
infections, which is now a global problem. Phage as a virus with specific recognition ability …

Using phage to drive selections toward restoring antibiotic sensitivity in Pseudomonas aeruginosa via chromosomal deletions

J Fujiki, K Nakamura, Y Ishiguro, H Iwano - Frontiers in Microbiology, 2024 - frontiersin.org
Phage therapy has re-emerged in modern medicine as a robust antimicrobial strategy in
response to the increasing prevalence of antimicrobial-resistant bacteria. However, bacterial …

[HTML][HTML] Phage P2-71 against multi-drug resistant Proteus mirabilis: isolation, characterization, and non-antibiotic antimicrobial potential

Z Dong, R Wu, L Liu, S Ai, J Yang, Q Li, K Fu… - Frontiers in Cellular …, 2024 - frontiersin.org
Proteus mirabilis, a prevalent urinary tract pathogen and formidable biofilm producer,
especially in Catheter-Associated Urinary Tract Infection, has seen a worrying rise in …