The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

Out of the wide range of calcium phosphate (CaP) biomaterials, calcium phosphate bone
cements (CPCs) have attracted increased attention since their discovery in the 1980s due to …

Calcium phosphates (CaPs) are widely accepted biomaterials able to promote the
regeneration of bone tissue. However, the regeneration of critical-sized bone defects has …

Objective The focus of this review is to summarize recent advances on regenerative
technologies (scaffolding matrices, cell/gene therapy and biologic drug delivery) to promote …

In early 1980s, researchers discovered self-setting calcium orthophosphate cements, which
are bioactive and biodegradable grafting bioceramics in the form of a powder and a liquid …

In this study, nano-hydroxyapatite scaffolds with high mechanical strength and an
interconnected porous structure were prepared using NTSS for the first time. The first step …

Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50.
The main clinical consequences are bone fractures, which often lead to patient disability or …

Bone nonunion may occur when the fracture is unstable, or blood supply is impeded. To
provide an effective treatment for the healing of nonunion defects, we introduce an injectable …

Calcium phosphate (CaP) bone cements are widely used for the treatment of bone defects
and have been proposed to serve as a delivery platform for therapeutic drugs, proteins and …

The development of injectable cement-like biomaterials via a minimally invasive approach
has always attracted considerable clinical interest for modern bone regeneration and repair …