Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses
LA Costa, N Eiro, M Fraile, LO Gonzalez, J Saá… - Cellular and Molecular …, 2021 - Springer
Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …
shown the therapeutic potential effect of MSC or their derived products. However, the …
Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
Biomaterials functionalized with MSC secreted extracellular vesicles and soluble factors for tissue regeneration
MÁ Brennan, P Layrolle… - Advanced functional …, 2020 - Wiley Online Library
The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …
Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent
Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …
Therapeutic properties of mesenchymal stromal/stem cells: the need of cell priming for cell-free therapies in regenerative medicine
Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …
Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
C Hu, L Zhao, L Zhang, Q Bao, L Li - Stem Cell Research & Therapy, 2020 - Springer
Various hepatoxic factors, such as viruses, drugs, lipid deposition, and autoimmune
responses, induce acute or chronic liver injury, and 3.5% of all worldwide deaths result from …
responses, induce acute or chronic liver injury, and 3.5% of all worldwide deaths result from …
The mesenchymal stem cell secretome as an acellular regenerative therapy for liver disease
J Driscoll, T Patel - Journal of gastroenterology, 2019 - Springer
The use of mesenchymal stem cells (MSC) for tissue repair has garnered much interest and
has been evaluated in several disease settings. Recent evidence indicates that the …
has been evaluated in several disease settings. Recent evidence indicates that the …
New therapeutic approaches of mesenchymal stem cells-derived exosomes
J Janockova, L Slovinska, D Harvanova… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem cells (MSCs) have been demonstrated to have a great potential in the
treatment of several diseases due to their differentiation and immunomodulatory capabilities …
treatment of several diseases due to their differentiation and immunomodulatory capabilities …
Current strategies to enhance adipose stem cell function: an update
Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety
of inflammatory disorders due to their multiple remarkable properties, such as superior …
of inflammatory disorders due to their multiple remarkable properties, such as superior …
Hypoxia-conditioned mesenchymal stem cells in tissue regeneration application
Mesenchymal stem cells (MSCs) have been demonstrated as promising cell sources for
tissue regeneration due to their capability of self-regeneration, differentiation, and …
tissue regeneration due to their capability of self-regeneration, differentiation, and …