[PDF][PDF] The role of CYP17A1 in prostate cancer development: structure, function, mechanism of action, genetic variations and its inhibition

MK Sivonova, J Jurecekova, Z Tatarkova… - Gen Physiol …, 2017 - researchgate.net
Androgens play an important role during the development of both normal prostate
epithelium and prostate cancer and variants of genes involved in androgen metabolism may …

[HTML][HTML] Prostate cancer: ESMO consensus conference guidelines 2012

A Horwich, J Hugosson, T de Reijke, T Wiegel… - Annals of oncology, 2013 - Elsevier
Abstract The first ESMO Consensus Conference on prostate cancer was held in Zurich,
Switzerland, on 17–19 November 2011, with the participation of a multidisciplinary panel of …

Prostate tumor growth and recurrence can be modulated by the ω-6: ω-3 ratio in diet: athymic mouse xenograft model simulating radical prostatectomy

UP Kelavkar, J Hutzley, R Dhir, P Kim, KGD Allen… - Neoplasia, 2006 - Elsevier
Evidence indicates that a diet rich in omega (ω)-6 polyunsaturated fatty acids (PUFAs)[eg,
linoleic acid (LA)] increases prostate cancer (PCa) risk, whereas a diet rich in ω-3 decreases …

Timing and choice of androgen ablation

D Kirk - Prostate cancer and prostatic diseases, 2004 - nature.com
Hormone therapy remains central to the management of advanced prostate cancer.
Evidence has accrued to suggest benefits from earlier treatment. Trials which demonstrate …

Immunohistochemical expression of Bcl2 is an independent predictor of time-to-biochemical failure in patients with clinically localized prostate cancer following radical …

K Revelos, C Petraki, A Gregorakis, A Scorilas… - Anticancer …, 2005 - ar.iiarjournals.org
Background: Whether the immunohistochemical expression (IHCE) of the bcl2, the p53 and
of the prostate apoptosis response-4 (PAR4) proteins is associated with preoperative PSA …

3D-QSAR and molecular docking studies on design anti-prostate cancer curcumin analogues

X Meng, L Cui, F Song, M Luan, J Ji… - … -Aided Drug Design, 2020 - ingentaconnect.com
Background: Prostate cancer is one of the most common tumors in the world and the fifth
leading cause of male cancer death. Although the treatment of localized androgen …

Prostate cancer relapse after therapy with curative intention: a diagnostic and therapeutic dilemma

E Gronau, M Goppelt, R Harzmann… - Oncology Research and …, 2005 - karger.com
Prostate cancer is the most common malignant disease and second in causes of cancer
death among men in Western Europe and North America. Despite improved surgical and …

Residual benign prostatic glands at the urethrovesical anastomosis after radical retropubic prostatectomy: prediction and impact on disease outcome

R Paul, M Hoppmann, H van Randenborgh, H Kübler… - European urology, 2004 - Elsevier
Objective: Biochemical failure after radical prostatectomy (RP) for localized prostate cancer
(PC) is the first evidence of disease recurrence. If residual benign prostatic glands are left …

Surgical treatment of localized prostate cancer

JE Damber, A Khatami - Acta Oncologica, 2005 - Taylor & Francis
Radical retropubic prostatectomy (RRP) is the reference method for treatment of localised,
organ confined prostate cancer. Since the introduction of nerve-sparing procedure for RRP …

[HTML][HTML] Impact of capsular incision on biochemical recurrence after radical perineal prostatectomy

KW Kwak, HM Lee, HY Choi - Prostate Cancer and Prostatic Diseases, 2010 - nature.com
The prognostic implications of capsular incision (CI) remain to be defined. We evaluated the
impact of CI on biochemical recurrence (BCR) and the potential risk factors of CI. Between …