A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

The spectrum of ischaemic cardiomyopathy, encompassing acute myocardial infarction to
congestive heart failure is a significant clinical issue in the modern era. This group of …

Summary Background Cardiosphere-derived cells (CDCs) reduce scarring after myocardial
infarction, increase viable myocardium, and boost cardiac function in preclinical models. We …

Background c-kit-positive, lineage-negative cardiac stem cells (CSCs) improve post-
infarction left ventricular (LV) dysfunction when administered to animals. We undertook a …

Objectives: This study sought to report full 1-year results, detailed magnetic resonance
imaging analysis, and determinants of efficacy in the prospective, randomized, controlled …

Cardiosphere‐derived cells (CDCs) have been shown to regenerate infarcted myocardium
in patients after myocardial infarction (MI). However, whether the cells of the newly formed …

Background—Cardiosphere-derived cells (CDCs) are an attractive cell type for tissue
regeneration, and autologous CDCs are being tested clinically. However, autologous …

Stem cells have the potential to differentiate into cardiovascular cell lineages and to
stimulate tissue regeneration in a paracrine/autocrine manner; thus, they have been …

A biomaterial system incorporating nanocellulose, poly (glycerol sebacate), and polypyrrole
is introduced for the treatment of myocardial infarction. Direct ink writing of the …

Cell delivery to the infarcted heart has emerged as a promising therapy, but is limited by very
low acute retention and engraftment of cells. The objective of this study was to compare a …