[HTML][HTML] Role of oxidative stress in reperfusion following myocardial ischemia and its treatments

M Xiang, Y Lu, L Xin, J Gao, C Shang, Z Jiang… - … medicine and cellular …, 2021 - hindawi.com
Myocardial ischemia is a disease with high morbidity and mortality, for which reperfusion is
currently the standard intervention. However, the reperfusion may lead to further myocardial …

[HTML][HTML] Cells of the immune system in cardiac remodeling: main players in resolution of inflammation and repair after myocardial infarction

I Kologrivova, M Shtatolkina, T Suslova… - Frontiers in …, 2021 - frontiersin.org
The burden of heart failure (HF), developing after myocardial infarction MI, still represents a
major issue in clinical practice. Failure of appropriate resolution of inflammation during post …

[HTML][HTML] Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway

J Zhang, L Huang, X Shi, L Yang, F Hua, J Ma… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Abstract Ischemia/reperfusion (I/R) injury is a life-threatening vascular emergency following
myocardial infarction. Our previous study showed cardioprotective effects of metformin …

[HTML][HTML] Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation

T Zhang, XF Wang, ZC Wang, D Lou, QQ Fang… - Biomedicine & …, 2020 - Elsevier
Aberrant scar formation, which includes keloid and hypertrophic scars, is associated with a
pathological disorganized wound healing process with chronic inflammation. The TGF …

USP22 protects against myocardial ischemia–reperfusion injury via the SIRT1-p53/SLC7A11–dependent inhibition of ferroptosis–induced cardiomyocyte death

S Ma, L Sun, W Wu, J Wu, Z Sun, J Ren - Frontiers in Physiology, 2020 - frontiersin.org
Myocardial ischemia–reperfusion (MI/R) injury is characterized by iron deposition and
reactive oxygen species production, which can induce ferroptosis. Ferroptosis has also been …

[HTML][HTML] Ferroptosis and its role in cardiomyopathy

D Li, W Pi, Z Sun, X Liu, J Jiang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Heart disease is the leading cause of death worldwide. Cardiomyopathy is a disease
characterized by the heart muscle damage, resulting heart in a structurally and functionally …

Macrophages in cardiac remodelling after myocardial infarction

J Yap, J Irei, J Lozano-Gerona, S Vanapruks… - Nature Reviews …, 2023 - nature.com
Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …

[HTML][HTML] Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls

WA Owens, A Walaszczyk, I Spyridopoulos… - Mechanisms of Ageing …, 2021 - Elsevier
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …

[HTML][HTML] Adverse cardiac remodelling after acute myocardial infarction: old and new biomarkers

AE Berezin, AA Berezin - Disease Markers, 2020 - hindawi.com
The prevalence of heart failure (HF) due to cardiac remodelling after acute myocardial
infarction (AMI) does not decrease regardless of implementation of new technologies …

Hirsutine, an emerging natural product with promising therapeutic benefits: a systematic review

MS Bhuia, P Wilairatana, J Ferdous, R Chowdhury… - Molecules, 2023 - mdpi.com
Fruits and vegetables are used not only for nutritional purposes but also as therapeutics to
treat various diseases and ailments. These food items are prominent sources of …