Dengue is one of the most typical viral infection categorized in the Neglected Tropical
Diseases (NTDs). It is transmitted via the female Aedes aegypti mosquito to humans and …

SIRT2, a cytoplasmic member of the Sirtuin family, has important roles in immunity and
inflammation. However, its function in regulating the response to DNA virus infection …

Guided by Global Natural Products Social molecular networking, two p-terphenyl derivatives
and one 4, 5-diphenyl-2-pyrone analogue, peniterphenyls A–C (1–3), together with five …

Enterovirus infections have become a serious public health threat to young children, leading
to hand-foot-and-mouth disease and more severe nervous system diseases. Due to the lack …

The human sirtuin 2 gene (SIRT2) encodes a full-length Sirt2 protein (ie, the Sirt2 isoform 1),
which primarily functions as a cytoplasmic α-tubulin deacetylase, and which promotes the …

Chronic hepatitis B (CHB) virus infection is one of the leading causes of cirrhosis and liver
cancer. Although the major drugs against CHB including nucleos (t) ide analogs and PEG …

SIRT2 is a member of NAD+-dependent sirtuins and its inhibition has been proposed as a
promising therapeutic approach for treating human diseases, including neurodegenerative …

Dengue is an acute tropical infectious disease transmitted by mosquitoes, which has posed
a major challenge to global public health. Unfortunately, there is a lack of clinically proven …

A colon tumor, one of the digestive tract malignant tumors, is harmful to human health. A
potential new treatment still deserves attention. The development of a new drug needs more …

Sirtuin 2 is a member of the sirtuin family nicotinamide adenine dinucleotide (NAD+)-
dependent deacetylases, known for its regulatory role in different processes, including …