Targeting the PI3K/mTOR pathway in idiopathic pulmonary fibrosis: Advances and therapeutic potential
Z Wang, Y Guo, K Li, Y Huo, S Wang, S Dong… - Bioorganic & Medicinal …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal lung disease characterized by
irreversible tissue scarring, leading to severe respiratory dysfunction. Despite current …
irreversible tissue scarring, leading to severe respiratory dysfunction. Despite current …
[HTML][HTML] Recent advances in the therapeutic potential of nobiletin against respiratory diseases
Y Qin, J Yang, H Li, J Li - Phytomedicine, 2024 - Elsevier
Nobiletin is a natural polymethoxylated flavonoid widely present in citrus fruit peels. It has
been extensively studied due to its wide range of pharmacological activities and considered …
been extensively studied due to its wide range of pharmacological activities and considered …
Integrated bioinformatics analysis for the identification of idiopathic pulmonary fibrosis–related genes and potential therapeutic drugs
Z Zhang, Q Guan, Y Tian, X Shao, P Zhao… - BMC Pulmonary …, 2023 - Springer
Objective The pathogenesis of idiopathic pulmonary fibrosis (IPF) remains unclear. We
sought to identify IPF-related genes that may participate in the pathogenesis and predict …
sought to identify IPF-related genes that may participate in the pathogenesis and predict …
A Pharmacokinetic Study of Sixteen Major Bioactive Components of Jinshui-Huanxian Granules in Pulmonary Fibrosis Model and Control Rats Using Orbitrap Fusion …
W Zhang, Y Wan, S Sun, Y Xie, D Zhao, B Li, J Li… - Molecules, 2023 - mdpi.com
Jinshui-Huanxian granules (JHGs), a Chinese herbal compound prescription, have shown a
therapeutic effect in reducing lung tissue damage, improving the degree of pulmonary …
therapeutic effect in reducing lung tissue damage, improving the degree of pulmonary …
Qingkailing granule alleviates pulmonary fibrosis by inhibiting PI3K/AKT and SRC/STAT3 signaling pathways
H Li, G Xin, Q Zhou, X Yu, C Wan, Y Wang, A Wen… - Bioorganic …, 2024 - Elsevier
Pulmonary fibrosis (PF) poses a significant challenge with limited treatment options and a
high mortality rate of approximately 45%. Qingkailing Granule (QKL), derived from the …
high mortality rate of approximately 45%. Qingkailing Granule (QKL), derived from the …
Global research status and trends of interactions between Traditional Chinese medicine and pulmonary fibrosis: A new dawn in treatment
B Wei, H Li, C Wang, J Hu - Heliyon, 2024 - cell.com
Background Pulmonary fibrosis (PF) remains a major sequela of COVID-19, yet its
pharmacotherapy remains unsatisfactory. Recently, Traditional Chinese medicine (TCM) …
pharmacotherapy remains unsatisfactory. Recently, Traditional Chinese medicine (TCM) …