Objectives Nephrotoxicity represents a major complication of vancomycin administration,
leading to high rates of morbidity and treatment failure. The aim of this meta-analysis was to …

Background Clinical practice guidelines or recommendations often require timely and
regular updating as new evidence emerges, because this can alter the risk-benefit trade-off …

The use of both old and new antimicrobials is increasingly important in combating the rise of
resistant organisms. Advances in technology, such as artificial intelligence, and alternative …

Background To date, outcome data with a large sample size and data regarding the clinical
outcomes of pharmacokinetic-guided (PK) dosing of vancomycin are limited. Aim We …

Currently, model-informed precision dosing uses one population pharmacokinetic model
that best fits the target population. We aimed to develop a subgroup identification-based …

Suboptimal antibiotic dosing has been identified as one of the key drivers in the
development of multidrug‐resistant (MDR) bacteria that have become a global health …

Objective: To evaluate the possibility of population-based dose optimization with the aid of
MwPharm modeling and to find the best model in the Windows version (WIN). Materials: 25 …

Introduction Current guidelines on vancomycin dosing lack specific recommendations about
its dosing in hematopoietic stem cell transplant (HSCT) patients, the objective of the current …

In a recent study in the present journal, nephrotoxicity induced by vancomycin in
combination therapy was reported [1]. Vancomycin-associated nephrotoxicity was found to …

Objectives This is a pilot retrospective study to assess the effect of glomerular hyper-filtration
(GHF) related to sickle cell disease (SCD) on vancomycin clearance and ultimately on …