The Development and Opportunities of Predictive Biotechnology
BM Nestl, BA Nebel, V Resch, M Schürmann… - …, 2024 - Wiley Online Library
Recent advances in bioeconomy allow a holistic view of existing and new process chains
and enable novel production routines continuously advanced by academia and industry. All …
and enable novel production routines continuously advanced by academia and industry. All …
[HTML][HTML] Enzyme engineering for biocatalysis
Contemporary Biocatalysis heavily relies on enzyme engineering as natural enzymes
frequently lack the requisite attributes for effective organic synthesis. The inherent limitations …
frequently lack the requisite attributes for effective organic synthesis. The inherent limitations …
Click, Compute, Create: A Review of Web‐based Tools for Enzyme Engineering
A Tripp, M Braun, F Wieser, G Oberdorfer… - …, 2024 - Wiley Online Library
Enzyme engineering, though pivotal across various biotechnological domains, is often
plagued by its time‐consuming and labor‐intensive nature. This review aims to offer an …
plagued by its time‐consuming and labor‐intensive nature. This review aims to offer an …
The multifaceted roles of COL4A4 in lung adenocarcinoma: An integrated bioinformatics and experimental study
T Zheng, Z Zheng, H Zhou, Y Guo, S Li - Computers in Biology and …, 2024 - Elsevier
Background Abnormal expression of collagen IV subunits has been reported in cancers, but
the significance is not clear. No study has reported the significance of COL4A4 in lung …
the significance is not clear. No study has reported the significance of COL4A4 in lung …
Rapid screening of multi-point mutations for enzyme thermostability modification by utilizing computational tools
J Jin, Q Meng, M Zeng, G Duan, E Wang… - Future Generation …, 2024 - Elsevier
Enzymes play an important role in industry due to their catalytic properties and
environmental friendliness. For application in harsh industrial environments, enzymes are …
environmental friendliness. For application in harsh industrial environments, enzymes are …
Combining Flexible Region Design and Automatic Design to Enhance the Thermal Stability and Catalytic Efficiency of Leucine Dehydrogenase
X Zhang, X Zhang, H Shi, H Zhang… - Journal of Agricultural …, 2024 - ACS Publications
Leucine dehydrogenase (LeuDH, EC 1.4. 1.9) can reversibly catalyze the oxidative
deamination of l-leucine and some other specific α-amino acids to form the corresponding α …
deamination of l-leucine and some other specific α-amino acids to form the corresponding α …
Engineering the activity and thermostability of a carboxylic acid reductase in the conversion of vanillic acid to vanillin
Y Ren, Z Qin, C Li, B Yuan, Y Yang, G Qu, Z Sun - Journal of Biotechnology, 2024 - Elsevier
Vanillin is a valuable natural product that can be used as a fragrance and additive. Recent
research in the biosynthesis of vanillin has brought attention to a key enzyme, carboxylic …
research in the biosynthesis of vanillin has brought attention to a key enzyme, carboxylic …
Microdroplet screening rapidly profiles a biocatalyst to enable its AI-assisted engineering
Engineering enzyme biocatalysts for higher efficiency is key to enabling sustainable, green
production processes for the chemical and pharmaceutical industry. This challenge can be …
production processes for the chemical and pharmaceutical industry. This challenge can be …