Tests are routinely used in medicine to screen for, diagnose, grade, and monitor the
progression of disease. Diagnostic information is obtained from a multitude of sources …

Background & Aims: Ultrasound-based transient elastography is a promising noninvasive
alternative to liver biopsy for detecting hepatic fibrosis. However, its overall test performance …

Background Although guidelines for critical appraisal of diagnostic research and meta-
analyses have already been published, these may be difficult to understand for clinical …

OBJECTIVE: To perform a meta-analysis to assess diagnostic characteristics of the CAGE in
screening for alcohol abuse or dependence in a general clinical population and to test a …

Background/objectives: Providing summary recommendations regarding self collection of
vaginal specimens for human papillomavirus (HPV) testing is difficult owing to the wide …

This unique book presents a framework for the strategy and methodology of diagnostic
research, in relation to its relevance for practice. Now in its second edition The Evidence …

Diagnostic tests are critical components of effective health care. They help determine
treatments that are most beneficial for a given patient. Their assessment is a complex …

Introduction Atrial fibrillation (AF) patients' major bleeding risk should be evaluated through
risk scores such as HAS-BLED, HEMORR2HAGES or ATRIA. These scores were validated …

This tutorial shows how to perform a meta-analysis of diagnostic test accuracy studies (DTA)
based on a 2× 2 table available for each included primary study. First, univariate methods for …

The Swedish Agency for Health Technology Assessment and Assessment of Social Services
(SBU) has recently published what they purported to be a systematic review of the literature …