Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …

Zebrafish offer many advantages that complement classic mammalian models for the study
of normal development as well as for the teratogenic effects of exposure to hazardous …

In order to localize the neural circuits involved in generating behaviors, it is necessary to
assign activity onto anatomical maps of the nervous system. Using brain registration across …

Dravet syndrome is a catastrophic pediatric epilepsy with severe intellectual disability,
impaired social development and persistent drug-resistant seizures. One of its primary …

Due to their well-characterized neural development and high genetic homology to
mammals, zebrafish (Danio rerio) have emerged as a powerful model organism in the field …

Neurodevelopmental disorders (NDDs) caused by aberrant brain growth and development
are life-long, debilitating illnesses that markedly impair the quality of life. Animal models are …

Tests with zebrafish embryos have gained wide acceptance as an alternative test model for
drug development and toxicity testing. In particular, the behavioral response of the zebrafish …

Zebrafish embryos and early larvae are becoming increasingly important as models in
biomedical research because of their low cost, high throughput and potential as a …

Seizures are characterized by hypersynchronization of neuronal networks. Understanding
these networks could provide a critical window for therapeutic control of recurrent seizure …

Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …