Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Effect of diet and dietary components on the composition of the gut microbiota

A Beam, E Clinger, L Hao - Nutrients, 2021 - mdpi.com
Diet and dietary components have profound effects on the composition of the gut microbiota
and are among the most important contributors to the alteration in bacterial flora. This review …

Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome

Y Kawano, M Edwards, Y Huang, AM Bilate, LP Araujo… - Cell, 2022 - cell.com
How intestinal microbes regulate metabolic syndrome is incompletely understood. We show
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …

The gut microbiota is associated with immune cell dynamics in humans

J Schluter, JU Peled, BP Taylor, KA Markey, M Smith… - Nature, 2020 - nature.com
The gut microbiota influences development,–and homeostasis,,–of the mammalian immune
system, and is associated with human inflammatory and immune diseases, as well as …

Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course

X Zhou, R Baumann, X Gao, M Mendoza, S Singh… - Cell, 2022 - cell.com
Changes in gut microbiota have been associated with several diseases. Here, the
International Multiple Sclerosis Microbiome Study (iMSMS) studied the gut microbiome of …

TH17 cell heterogeneity and its role in tissue inflammation

A Schnell, DR Littman, VK Kuchroo - Nature immunology, 2023 - nature.com
Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …

Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease

C García-Montero, O Fraile-Martínez… - Nutrients, 2021 - mdpi.com
The most prevalent diseases of our time, non-communicable diseases (NCDs)(including
obesity, type 2 diabetes, cardiovascular diseases and some types of cancer) are rising …

The gut–joint axis in rheumatoid arthritis

MM Zaiss, HJ Joyce Wu, D Mauro, G Schett… - Nature Reviews …, 2021 - nature.com
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder that primarily
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …

[HTML][HTML] Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells

QY Ang, M Alexander, JC Newman, Y Tian, J Cai… - Cell, 2020 - cell.com
Very low-carbohydrate, high-fat ketogenic diets (KDs) induce a pronounced shift in
metabolic fuel utilization that elevates circulating ketone bodies; however, the …