Combining existing drug therapy is essential in developing new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …

Alzheimer's disease (AD) is the most common form of age‐related dementia, characterized
by progressive memory loss and cognitive disturbances. The hippocampus, where adult …

Diabetic wound (DW) therapy is currently a big challenge in medicine and strategies to
enhance neurogenesis and angiogenesis have appeared to be a promising direction …

Aging is the primary risk factor for most neurodegenerative diseases, including Alzheimer's
disease. Major hallmarks of brain aging include neuroinflammation/immune activation and …

Epidermal growth factor receptor (EGFR) plays a pivotal role in early brain development,
although its expression pattern declines in accordance with the maturation of the active …

Cognitive impairment has been associated with an age-related decline in adult hippocampal
neurogenesis (AHN). The molecular basis of declining neurogenesis in the aging …

Background & aims The interaction between diet, inflammation, and oxidative stress
significantly influences aging, but the available evidence has been limited. We evaluated …

Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by
irreversible cognitive declines. Senile plaques formed by amyloid-β (Aβ) peptides and …

Adult neurogenesis is a multistage process during which newborn neurons are generated
through the activation and proliferation of neural stem cells (NSCs) and integrated into …

Decreased adult neurogenesis, or the gradual depletion of neural stem cells in adult
neurogenic niches, is considered a hallmark of brain aging. This review provides a …