Neutrophils actively contribute to obesity-associated inflammation and pathological complications

E Uribe-Querol, C Rosales - Cells, 2022 - mdpi.com
Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

[HTML][HTML] Neutrophils in psoriasis

CC Chiang, WJ Cheng, M Korinek, CY Lin… - Frontiers in …, 2019 - frontiersin.org
Neutrophils are the most abundant innate immune cells. The pathogenic roles of neutrophils
are related to chronic inflammation and autoimmune diseases. Psoriasis is a chronic …

Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity

DS Wilson, S Hirosue, MM Raczy, L Bonilla-Ramirez… - Nature materials, 2019 - nature.com
Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies
(humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a …

[HTML][HTML] A versatile high-throughput assay to characterize antibody-mediated neutrophil phagocytosis

CB Karsten, N Mehta, SA Shin, TJ Diefenbach… - Journal of …, 2019 - Elsevier
Neutrophils, the most abundant white blood cell, play a critical role in anti-pathogen
immunity via phagocytic clearance, secretion of enzymes and immunomodulators, and the …

NETosis contributes to the pathogenesis of diabetes and its complications

R Njeim, WS Azar, AH Fares, ST Azar… - Journal of …, 2020 - jme.bioscientifica.com
NETosis, a novel form of neutrophil-related cell death, acts as a major regulator of diabetes
and diabetes-associated complications. In this review, we show that the extrusion of …

Pathophysiology and molecular imaging of diabetic foot infections

K Rubitschung, A Sherwood, AP Crisologo… - International journal of …, 2021 - mdpi.com
Diabetic foot infection is the leading cause of non-traumatic lower limb amputations
worldwide. In addition, diabetes mellitus and sequela of the disease are increasing in …

[HTML][HTML] Roles of neutrophils in glioma and brain metastases

YJ Lin, KC Wei, PY Chen, M Lim… - Frontiers in immunology, 2021 - frontiersin.org
Neutrophils, which are the most abundant circulating leukocytes in humans, are the first line
of defense against bacterial and fungal infections. Recent studies have reported the role and …

Lung targeted liposomes for treating ARDS

SA Raviv, M Alyan, E Egorov, A Zano… - Journal of controlled …, 2022 - Elsevier
Abstract Acute Respiratory Distress Syndrome (ARDS), associated with Covid-19 infections,
is characterized by diffuse lung damage, inflammation and alveolar collapse that impairs …

An update review of globally reported SARS-CoV-2 vaccines in preclinical and clinical stages

H Motamedi, MM Ari, S Dashtbin, M Fathollahi… - International …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the rapidly spreading pandemic COVID-19 in the world. As an effective therapeutic strategy …

[HTML][HTML] For better or for worse: a look into neutrophils in traumatic spinal cord injury

S Zivkovic, M Ayazi, G Hammel, Y Ren - Frontiers in cellular …, 2021 - frontiersin.org
Neutrophils are short-lived cells of the innate immune system and the first line of defense at
the site of an infection and tissue injury. Pattern recognition receptors on neutrophils …