Yigansan ameliorates maternal immune activation-induced autism-like behaviours by regulating the IL-17A/TRAF6/MMP9 pathway: network analysis and …

L Fan, X Zeng, Y Jiang, D Zheng, H Wang, Q Qin, M Li… - Phytomedicine, 2024 - Elsevier
Background Maternal immune activation (MIA) is a significant factor inducing to autism
spectrum disorders (ASD) in offspring. The fundamental principle underlying MIA is that …

IGFBP1 stabilizes Umod expression through m6A modification to inhibit the occurrence and development of cystitis by blocking NF-κB and ERK signaling pathways

Z Yuan, W Wang, S Song, Y Ling, J Xu, Z Tao - International …, 2024 - Elsevier
Cystitis is a common disease closely associated with urinary tract infections, and the specific
mechanisms underlying its occurrence and development remain largely unknown. In this …

The prenatal use of agmatine prevents social behavior deficits in VPA‐exposed mice by activating the ERK/CREB/BDNF signaling pathway

S Chen, Q Xu, L Zhao, M Zhang, H Xu - Birth Defects Research, 2024 - Wiley Online Library
Background According to reports, prenatal exposure to valproic acid can induce autism
spectrum disorder (ASD)‐like symptoms in both humans and rodents. However, the exact …

[HTML][HTML] Adenosine A2A Receptor in Bone Marrow-Derived Cells Mediated Macrophages M2 Polarization via PPARγ-P65 Pathway in Chronic Hypoperfusion Situation

KJ Mou, KF Shen, YL Li, ZF Wu… - Frontiers in Aging …, 2022 - frontiersin.org
Background: The role of adenosine A2A receptor (A2AR) in the ischemic white matter
damage induced by chronic cerebral hypoperfusion remains obscure. Here we investigated …

Neuroblast differentiation-associated protein derived polypeptides: AHNAK (5758-5775) induces inflammation by activating mast cells via ST2

X Song, L Zhang, X Du, Y Zheng, T Jia… - Immunological …, 2023 - Taylor & Francis
Psoriasis is a chronic inflammatory skin disease. Mast cells are significantly increased and
activated in psoriatic lesions and are involved in psoriatic inflammation. Some endogenous …

Exploring the role of interleukin-27 as a regulator of neuronal survival in central nervous system diseases

AN Nortey, KN Garces, AS Hackam - Neural regeneration …, 2022 - journals.lww.com
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell
stress, neuronal disease, and tumors. Recent studies in various tissues indicate that …

[PDF][PDF] Peripheral expression of ADORA2A is increased and is correlated with Autism Spectrum Disorder Severity in a sample of turkish children

H Akköprü, A Alnak… - Psychiatry and …, 2023 - psychiatry-psychopharmacology …
Background: The aim of this study was to evaluate the peripheral expression of ADORA2A
(Adenosine A2A receptor gene) in young subjects with autism spectrum disorder compared …

Purinergic Signaling in Autism Spectrum Disorder

I Deckmann, J Santos-Terra, C Gottfried - Purinergic Signaling in …, 2023 - Springer
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder
estimated to affect 1: 36 individuals, characterized by impairments in the social approach …

Over-expressed LOC101927196 suppressed oxidative stress levels and neuron cell proliferation in a rat model of autism through disrupting the Wnt signaling pathway …

W Yao, J Huang, H He - Cellular signalling, 2019 - Elsevier
Accumulating evidence indicates that long non-coding RNAs (lncRNAs) play an important
role in autism. Herein, we delineated the functions of LOC101927196 and its potential …

探索白细胞介素27 在中枢神经系统疾病中作为神经元存活调节剂的作用

AN Nortey, KN Garces, AS Hackam - 中国神经再生研究(英文版), 2022 - sjzsyj.com.cn
Interleukin-27 is a pleiotropic cytokine that is involved in tissue responses to infection, cell
stress, neuronal disease, and tumors. Recent studies in various tissues indicate that …