Lung cancer is primary cancer threatening human life worldwide with the highest mortality
rate. The early detection of lung cancer plays a critical role in the early diagnosis and …

As well-appreciated biomarkers, tumor markers have been spotlighted as reliable tools for
predicting the behavior of different tumors and helping clinicians ascertain the type of …

BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …

There is experimental evidence that volatile substances in human breath can reflect
presence of neoplasma. Volatile aldehydes were determined in exhaled breath of 12 lung …

Glycoconjugates constitute a major class of biomolecules which include glycoproteins,
glycosphingolipids and proteoglycans. Glycans are involved in several physiological and …

The cytoprotective keratins (K) compose the intermediate filaments of epithelial cells and
their inherited and spontaneous mutations give rise to keratinopathies. For example …

Lung cancer is sometimes difficult to differentiate from benign lung diseases expressing
nodular shadow in imaging study. We assessed the diagnostic value of two commonly used …

The second cause of death in the world has been reported to be cancer, and it has been on
the rise in recent years. As a result of the difficulties of cancer detection and its treatment, the …

BACKGROUND: Up to now, none of the breath biomarkers or marker sets proposed for
cancer recognition has reached clinical relevance. Possible reasons are the lack of …

Cancer is a leading cause of death. Early detection is usually associated with better clinical
outcomes. Recent advances in genomics and proteomics raised hopes that new biomarkers …