Pulmonary surfactant is a critical component of lung function in healthy individuals. It
functions in part by lowering surface tension in the alveoli, thereby allowing for breathing …

Prolonged, low-dose glucocorticoids (GCs) have shown the highest efficacy among
pharmacological and non-pharmacological treatments for COVID-19. Despite the World …

How acute respiratory distress syndrome progresses from underlying disease or trauma is
poorly understood, and there are no generally accepted treatments resulting in a 40 …

Background: Automated segmentation of COVID-19 infection lesions and the assessment of
the severity of the infections are critical in COVID-19 diagnosis and treatment. Based on a …

SARS-CoV-2 directly targets alveolar epithelial cells and can lead to surfactant deficiency.
Early reports suggested surfactant replacement may be effective in improving outcomes. The …

Key Clinical Message Recently spontaneous tension pneumomediastinum (STM), were
reported as infrequent complications in coronavirus disease 2019 (COVID‐19) patients but …

Background: The diagnosis of COPD is based on both clinical signs and functional tests.
Although there are different functional tests used to assess COPD, no reliable biomarkers …

SARS-CoV-2, a single stranded positive RNA-virus, emerged in 2019 and caused a global
pandemic. Some infected patients develop severe complications, such as acute respiratory …

The COVID-19 pandemic was an unprecedented global crisis that significantly impacted
around the world. The dramatic surge of COVID-19 patients forced healthcare systems to …

Aims: We developed an international registry to examine cardiovascular complications of
COVID-19. Methods: A REDCap form was created in March 2020 at Mayo Clinic in …