[HTML][HTML] Signaling pathways and targeted therapy for myocardial infarction
Q Zhang, L Wang, S Wang, H Cheng, L Xu… - Signal transduction and …, 2022 - nature.com
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
worldwide disease with high morbidity and high mortality. Whilst there is still a long way to …
[HTML][HTML] Targeting the Wnt/β-catenin signaling pathway in cancer
Y Zhang, X Wang - Journal of hematology & oncology, 2020 - Springer
The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell
proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy …
proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy …
Wnt signaling pathway: A comprehensive review
Wnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical
for a variety of physiological processes of an organism's body, including stem cell …
for a variety of physiological processes of an organism's body, including stem cell …
[HTML][HTML] Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …
[HTML][HTML] Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness …
Cancer is still the leading cause of death globally. The approval of the therapeutic use of
monoclonal antibodies against immune checkpoint molecules, notably those that target the …
monoclonal antibodies against immune checkpoint molecules, notably those that target the …
Role of goblet cells in intestinal barrier and mucosal immunity
S Yang, M Yu - Journal of inflammation research, 2021 - Taylor & Francis
Goblet cells and the mucus they secrete serve as an important barrier, preventing pathogens
from invading the mucosa to cause intestinal inflammation. The perspective regarding goblet …
from invading the mucosa to cause intestinal inflammation. The perspective regarding goblet …
[HTML][HTML] Molecular markers and targets in melanoma
C Teixido, P Castillo, C Martinez-Vila, A Arance, L Alos - Cells, 2021 - mdpi.com
Melanoma develops as a result of several genetic alterations, with UV radiation often acting
as a mutagenic risk factor. Deep knowledge of the molecular signaling pathways of different …
as a mutagenic risk factor. Deep knowledge of the molecular signaling pathways of different …
[HTML][HTML] The Wnt signalling pathway: a tailored target in cancer
M Koni, V Pinnarò, MF Brizzi - International Journal of Molecular Sciences, 2020 - mdpi.com
Cancer is one of the greatest public health challenges. According to the World Health
Organization (WHO), 9.6 million cancer deaths have been reported in 2018. The most …
Organization (WHO), 9.6 million cancer deaths have been reported in 2018. The most …
[HTML][HTML] LRP5 and LRP6 in Wnt signaling: similarity and divergence
Q Ren, J Chen, Y Liu - Frontiers in cell and developmental biology, 2021 - frontiersin.org
The canonical Wnt/β-catenin signaling plays a fundamental role in regulating embryonic
development, injury repair and the pathogenesis of human diseases. In vertebrates, low …
development, injury repair and the pathogenesis of human diseases. In vertebrates, low …
The multidimensional role of the Wnt/β‐catenin signaling pathway in human malignancies
Several signaling pathways have been identified as important for developmental processes.
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …