PGC1α: friend or foe in cancer?
F Mastropasqua, G Girolimetti, M Shoshan - Genes, 2018 - mdpi.com
The PGC1 family (Peroxisome proliferator-activated receptor γ (PPARγ) coactivators) of
transcriptional coactivators are considered master regulators of mitochondrial biogenesis …
transcriptional coactivators are considered master regulators of mitochondrial biogenesis …
Mitochondria participate in chemoresistance to cisplatin in human ovarian cancer cells
LX Zampieri, D Grasso, C Bouzin, D Brusa… - Molecular Cancer …, 2020 - AACR
Ovarian cancer is an aggressive disease that affects about 300,000 patients worldwide, with
a yearly death count of about 185,000. Following surgery, treatment involves adjuvant or …
a yearly death count of about 185,000. Following surgery, treatment involves adjuvant or …
Mitochondria in oral cancer stem cells: Unraveling the potential drug targets for new and old drugs
I Olmedo, D Martínez, J Carrasco-Rojas, JA Jara - Life Sciences, 2023 - Elsevier
Head and neck cancer is a major health problem worldwide, with most cases arising in the
oral cavity. Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer …
oral cavity. Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer …
Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer
The evolution of resistance in high-grade serous ovarian cancer (HGSOC) cells following
chemotherapy is only partially understood. To understand the selection of factors driving …
chemotherapy is only partially understood. To understand the selection of factors driving …
Anticancer activity of broccoli, its organosulfur and polyphenolic compounds
A Gasmi, A Gasmi Benahmed, M Shanaida… - Critical Reviews in …, 2023 - Taylor & Francis
The use of natural bioactive constituents from various food sources for anticancer purposes
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …
has become increasingly popular worldwide. Broccoli (Brassica oleracea var. italica) is on …
Methods to evaluate changes in mitochondrial structure and function in cancer
Simple Summary Mitochondria, which play crucial roles in energy production and in
maintaining cellular homeostasis, are potential therapeutic targets in a variety of diseases …
maintaining cellular homeostasis, are potential therapeutic targets in a variety of diseases …
[HTML][HTML] Cancer stem cells, epithelial-mesenchymal transition, ATP and their roles in drug resistance in cancer
H Zhang, A Steed, M Co, X Chen - Cancer Drug Resistance, 2021 - ncbi.nlm.nih.gov
The cancer stem cell (CSC) state and epithelial-mesenchymal transition (EMT) activation are
tightly interconnected. Cancer cells that acquire the EMT/CSC phenotype are equipped with …
tightly interconnected. Cancer cells that acquire the EMT/CSC phenotype are equipped with …
Mitochondria-centric bioenergetic characteristics in cancer stem-like cells
Metabolic and genotoxic stresses that arise during tumor progression and anti-cancer
treatment, respectively, can impose a selective pressure to promote cancer evolution in the …
treatment, respectively, can impose a selective pressure to promote cancer evolution in the …
CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α
X Fu, Q Zhang, Z Wang, Y Xu, Q Dong - Cell Death & Disease, 2024 - nature.com
Ovarian cancer is the most lethal malignancy among gynecologic cancers, and primary and
secondary chemotherapy resistance is one of the important reasons for poor prognosis of …
secondary chemotherapy resistance is one of the important reasons for poor prognosis of …
Metabolic reprogramming of the tumor immune microenvironment in ovarian cancer: A novel orientation for immunotherapy
Y Lin, X Zhou, Y Ni, X Zhao, X Liang - Frontiers in Immunology, 2022 - frontiersin.org
Ovarian cancer is the most lethal gynecologic tumor, with the highest mortality rate.
Numerous studies have been conducted on the treatment of ovarian cancer in the hopes of …
Numerous studies have been conducted on the treatment of ovarian cancer in the hopes of …