Exosome-mediated antigen delivery: unveiling novel strategies in viral infection control and vaccine design

D El Safadi, A Mokhtari, M Krejbich, A Lagrave… - Vaccines, 2024 - mdpi.com
Exosomes are small subtypes of extracellular vesicles (EVs) naturally released by different
types of cells into their environment. Their physiological roles appear to be multiple, yet …

Selective Termination of Autophagy-Dependent Cancers

A Roy, ML DePamphilis - Cells, 2024 - mdpi.com
The goal of cancer research is to identify characteristics of cancer cells that allow them to be
selectively eliminated without harming the host. One such characteristic is autophagy …

Autophagic degradation of DHCR7 activates AKT3 and promotes sevoflurane-induced hippocampal neuroinflammation in neonatal mice

Q Hou, J Yuan, S Li, J Ma, W Li, B Zhang… - Free Radical Biology …, 2024 - Elsevier
Repeated sevoflurane exposure in neonatal mice triggers neuroinflammation with
detrimental effects on cognitive function. Yet, the mechanism of the sevoflurane-induced …

A PI (3, 5) P2/ESCRT-III axis terminates STING signalling by facilitating TSG101-mediated lysosomal microautophagy

T Taguchi, T Shoji, A Shinojima, S Kusumi, D Koga… - bioRxiv, 2024 - biorxiv.org
Stimulator of interferon genes (STING) is critical for the type I interferon response to
pathogen-or self-derived cytosolic DNA. STING is degraded by the endosomal sorting …