AgRP neurons coordinate the mitigation of activity-based anorexia

AK Sutton Hickey, SC Duane, LE Mickelsen… - Molecular …, 2023 - nature.com
Anorexia nervosa (AN) is a debilitating and deadly disease characterized by low body mass
index due to diminished food intake, and oftentimes concurrent hyperactivity. A high …

Galvanic Redox Potentiometry for Fouling‐Free and Stable Serotonin Sensing in a Living Animal Brain

F Zhu, Y Xue, W Ji, X Li, W Ma, P Yu… - Angewandte …, 2023 - Wiley Online Library
Abstract Serotonin (5‐HT) is a major neurotransmitter broadly involved in many aspects of
feeling and behavior. Although its electro‐activity makes it a promising candidate for …

[HTML][HTML] Current Discoveries and Future Implications of Eating Disorders

B Feng, J Harms, E Chen, P Gao, P Xu… - International Journal of …, 2023 - mdpi.com
Eating disorders (EDs) are characterized by severe disturbances in eating behaviors and
can sometimes be fatal. Eating disorders are also associated with distressing thoughts and …

A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger

X Cui, Q Tong, H Xu, C Xie, L Xiao - Progress in Neurobiology, 2023 - Elsevier
Dopamine (DA) signal play pivotal roles in regulating motivated behaviors, including feeding
behavior, but the role of midbrain DA neurons in modulating food intake and neural circuitry …

[HTML][HTML] Dorsal raphe serotonergic neurons suppress feeding through redundant forebrain circuits

I Aklan, N Sayar-Atasoy, F Deng, H Kim, Y Yavuz… - Molecular …, 2023 - Elsevier
Objective Serotonin (5HT) is a well-known anorexigenic molecule, and 5HT neurons of
dorsal raphe nucleus (DRN) have been implicated in suppression of feeding; however, the …

Dynamic changes in the central autonomic network of patients with anorexia nervosa

F de la Cruz, A Schumann, S Suttkus… - European Journal of …, 2023 - Wiley Online Library
Autonomic cardiac dysfunction is a common complication in patients with anorexia nervosa
(AN). Despite its high prevalence, physicians often overlook this clinical condition, and little …

Dopamine neurons in the ventral tegmental area modulate REM sleep

JJ Fraigne, PH Luppi, CE Mahoney, R De Luca… - Sleep, 2023 - academic.oup.com
The discovery of REM sleep is attributed to the landmark observations of Eugene Aserinsky
and Nathaniel Kleitman. In 1953, they identified periods of „active sleep‟ that are marked by …

新型哌啶-4-醇衍生物的合成及生物活性.

孙海洋, 杨晓宁, 李晖, 王佳毅… - Chinese Journal of …, 2023 - search.ebscohost.com
发现具有新作用方式的农药对于现代作物保护至关重要. 本研究以哌啶醇和邻苯二酚为起始原料
, 经5 步反应制备得到了一系列新型的哌啶-4-醇衍生物, 并通过核磁共振氢谱 …

An Excitatory Projection from the Basal Forebrain to the Ventral Tegmental Area Underlying Anorexia-like Phenotypes

J Cai, Y Xu, Z Jiang, Y Jiang, C Young, H Li… - bioRxiv, 2023 - biorxiv.org
Adaptation to potential environmental threat cues in feeding regulation is key for animal
survival. Maladaptation in balancing internal energy needs and external threat cues may …

Hyperactivity of a midbrain dopamine to 5-HT circuit causes anorexia

H Liu, X Cai, Y He, Y Xu - Journal of Molecular Cell Biology, 2022 - academic.oup.com
Anorexia nervosa (AN) is a severe eating disorder that can eventually lead to death, but
effective therapies are missing due to a lack of knowledge about its pathophysiology …