HIV-1 integrase inhibitors: a comparative review of efficacy and safety
KK Scarsi, JP Havens, AT Podany, SN Avedissian… - Drugs, 2020 - Springer
The newest class of antiretrovirals for all persons living with HIV are the integrase strand
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
transfer inhibitors (INSTIs). Since 2007, five INSTIs have been introduced: raltegravir …
Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors
AT Podany, KK Scarsi, CV Fletcher - Clinical pharmacokinetics, 2017 - Springer
Abstract Dolutegravir (DTG), elvitegravir (EVG) and raltegravir (RAL) are members of the
latest class of antiretrovirals (ARVs) that have become available to treat human …
latest class of antiretrovirals (ARVs) that have become available to treat human …
Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV
Objective: To evaluate dolutegravir pharmacokinetics during pregnancy compared with
postpartum and in infant washout samples after delivery. Design: Ongoing, nonrandomized …
postpartum and in infant washout samples after delivery. Design: Ongoing, nonrandomized …
Comparative clinical pharmacokinetics and pharmacodynamics of HIV-1 integrase strand transfer inhibitors: an updated review
Abstract Bictegravir, cabotegravir, dolutegravir, elvitegravir, and raltegravir are members of
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
the latest class of antiretrovirals available to treat human immunodeficiency virus (HIV) …
HIV-1 integrase strand transfer inhibitors and neurodevelopment
Children born to mothers, with or at risk, of human immunodeficiency virus type-1 (HIV-1)
infection are on the rise due to affordable access of antiretroviral therapy (ART) to pregnant …
infection are on the rise due to affordable access of antiretroviral therapy (ART) to pregnant …
Raltegravir versus efavirenz in antiretroviral-naive pregnant women living with HIV (NICHD P1081): an open-label, randomised, controlled, phase 4 trial
EC João, RL Morrison, DE Shapiro, N Chakhtoura… - The Lancet …, 2020 - thelancet.com
Background Although antiretroviral regimens containing integrase inhibitors rapidly
suppress HIV viral load in non-pregnant adults, few published data from randomised …
suppress HIV viral load in non-pregnant adults, few published data from randomised …
Uptake and discontinuation of integrase inhibitors (INSTIs) in a large cohort setting
Background: Despite increased integrase strand transfer inhibitor (INSTI) use, limited large-
scale, real-life data exists on INSTI uptake and discontinuation. Setting: International …
scale, real-life data exists on INSTI uptake and discontinuation. Setting: International …
Pharmacokinetics of HIV-integrase inhibitors during pregnancy: mechanisms, clinical implications and knowledge gaps
R van der Galiën, R Ter Heine, R Greupink… - Clinical …, 2019 - Springer
Prevention of mother-to-child transmission of HIV and optimal maternal treatment are the
most important goals of antiretroviral therapy in pregnant women with HIV. These goals may …
most important goals of antiretroviral therapy in pregnant women with HIV. These goals may …
Integrase inhibitors in late pregnancy and rapid HIV viral load reduction
L Rahangdale, J Cates, JN Potter, ML Badell… - American journal of …, 2016 - Elsevier
Background Minimizing time to HIV viral suppression is critical in pregnancy. Integrase
strand transfer inhibitors (INSTIs), like raltegravir, are known to rapidly suppress plasma HIV …
strand transfer inhibitors (INSTIs), like raltegravir, are known to rapidly suppress plasma HIV …
[图书][B] Pharmacology Research And Textbook 2: HIV-1 Integrase Inhibitors, Coenzyme Q10, and Ferroptosis
Page 1 Pharmacology Research And Textbook 2 Chapter1: HIV-1 Integrase Inhibitors and
Neurodevelopment Chapter2: Coenzyme Q10 Chapter3: Ferroptosis Author in Chief …
Neurodevelopment Chapter2: Coenzyme Q10 Chapter3: Ferroptosis Author in Chief …