How we treat primary immune thrombocytopenia in adults

X Liu, Y Hou, M Hou - Journal of Hematology & Oncology, 2023 - Springer
Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder
characterized by decreased platelet counts and an increased risk of bleeding. Multiple …

Celiac disease and thrombotic events: systematic review of published cases

N Pantic, I Pantic, D Jevtic, V Mogulla, S Oluic… - Nutrients, 2022 - mdpi.com
Extraintestinal manifestations of celiac disease (CD) should be considered, even in patients
without typical intestinal symptoms. The aim of our study is to examine the literature …

[HTML][HTML] EHA guidelines on management of antithrombotic treatments in thrombocytopenic patients with cancer

A Falanga, A Leader, C Ambaglio, Z Bagoly… - …, 2022 - journals.lww.com
In cancer patients, thrombocytopenia can result from bone marrow infiltration or from
anticancer medications and represents an important limitation for the use of antithrombotic …

[HTML][HTML] Platelet ageing: A review

HE Allan, A Vadgama, PC Armstrong, TD Warner - Thrombosis Research, 2023 - Elsevier
Platelet ageing is an area of research which has gained much interest in recent years.
Newly formed platelets, often referred to as reticulated platelets, young platelets or immature …

Expert Report on Immune Thrombocytopenia: Current Diagnostics and Treatment–Recommendations from an Expert Group from Austria, Germany, and Switzerland

A Matzdorff, SR Alesci, J Gebhart… - Oncology Research …, 2023 - karger.com
Immune thrombocytopenia (ITP) is a rare and orphan disease. The following
recommendations are meant to assist physicians, dentists, and other health-care …

[HTML][HTML] Evaluation of the procoagulant state in chronic immune thrombocytopenia before and after eltrombopag treatment—a prospective cohort study

WEM van Dijk, GC Poolen, A Huisman… - Journal of Thrombosis …, 2023 - Elsevier
Background Thrombopoietin receptor agonists are frequently used in treating immune
thrombocytopenia (ITP) owing to high response rates and good tolerability. ITP is associated …

Risk‐based and individualised management of bleeding and thrombotic events in adults with primary immune thrombocytopenia (ITP)

C Lambert, H Maitland… - European Journal of …, 2024 - Wiley Online Library
Although bleeding is one of the main symptoms of primary immune thrombocytopenia (ITP),
risk factors for bleeding have yet to be fully established. Low platelet count (PC;< 20–30× …

Recent progress in ITP treatment

F Rodeghiero - International Journal of Hematology, 2023 - Springer
In this review, the recently approved drugs avatrombopag and fostamatinib, which were not
extensively covered within 2019 international recommendations for ITP, will be discussed in …

Fibrinogenolysis and fibrinolysis in vaccine-induced immune thrombocytopenia and thrombosis

M Simpson, A Narwal, E West, J Martin… - Journal of Thrombosis …, 2023 - Elsevier
Background Vaccine-induced immune thrombocytopenia and thrombosis (VITT) is a rare
syndrome associated with adenoviral vector vaccines for COVID-19. The syndrome is …

Molecular pathogenesis of endotheliopathy and endotheliopathic syndromes, leading to inflammation and microthrombosis, and various hemostatic clinical …

JC Chang - Medicina, 2022 - mdpi.com
Endotheliopathy, according to the “two-activation theory of the endothelium”, can be
triggered by the activated complement system in critical illnesses, such as sepsis and …