Background Daclizumab high-yield process (HYP) is a humanized monoclonal antibody that
binds to CD25 (alpha subunit of the interleukin-2 receptor) and modulates interleukin-2 …

Obesity is associated with low-grade chronic inflammation. Indeed, adipose tissues (AT) in
obese individuals are the former site of progressive infiltration by pro-inflammatory immune …

Autoimmune disease, caused by unwanted immune responses to self-antigens, affects
millions of people each year and poses a great social and economic burden to individuals …

Autoimmune disorders (ADs) are multifactorial diseases involving, genetic, epigenetic, and
environmental factors characterized by an inappropriate immune response toward self …

Pro-inflammatory T cells in the central nervous system (CNS) are causally associated with
multiple demyelinating and neurodegenerative diseases,,,,–, but the pathways that control …

Background Daclizumab, a humanised monoclonal antibody, modulates interleukin-2
signalling by blocking the α subunit (CD25) of the interleukin-2 receptor. We assessed …

In recent years, microRNAs (miRNAs) have gained increased attention from researchers
around the globe. Although it is twenty nucleotides long, it can modulate several gene …

The mammalian intestine harbors trillions of beneficial commensal bacteria that are
essential for the development of the immune system and for maintenance of physiologic …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …

A functional immune system is essential for healthy life. This is achieved by the coordinate
activation and interaction of different immune cells. One should be aware that activation of …