Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous
system (CNS) resulting from a breakdown in peripheral immune tolerance. Although a …

Recent advances in understanding how the mammalian immune system and intestinal
microbiota functionally interact have yielded novel insights for human health and disease …

Multiple sclerosis (MS) is the most common inflammatory disorder of the central nervous
system (CNS) in young adults. When MS is not treated, it leads to irreversible and severe …

Innate lymphoid cells (ILCs) play a central role in the response to infection by secreting
cytokines crucial for immune regulation, tissue homeostasis, and repair. Although …

The treatment landscape for relapsing forms of multiple sclerosis (RMS) has expanded
considerably over the last 10 years with the approval of multiple new disease-modifying …

Innate lymphoid cells (ILCs) are innate immune cells that are ubiquitously distributed in
lymphoid and nonlymphoid tissues and enriched at mucosal and barrier surfaces. Three …

Immunosuppression strategies that selectively inhibit effector T cells while preserving and
even enhancing CD4+FOXP3+ regulatory T cells (Treg) permit immune self-regulation and …

Innate lymphoid cells (ILC) are a heterogeneous group of cellular subsets that produce large
amounts of T cell–associated cytokines in response to innate stimulation in the absence of …

Tissue-resident immune cells reside in distinct niches across organs, where they contribute
to tissue homeostasis and rapidly respond to perturbations in the local microenvironment …

Objective: To characterize changes in myeloid and lymphoid innate immune cells in patients
with relapsing-remitting multiple sclerosis (MS) during a 6-month follow-up after …