Human innate lymphoid cells (ILCs): toward a uniform immune‐phenotyping

S Trabanelli, A Gomez‐Cadena… - Cytometry Part B …, 2018 - Wiley Online Library
Helper innate lymphoid cells (ILCs), the most recently identified population of the ILC family,
play a fundamental role in the restoration of tissue integrity, in the protection against …

Maintenance of immune homeostasis through ILC/T cell interactions

N von Burg, G Turchinovich, D Finke - Frontiers in immunology, 2015 - frontiersin.org
Innate lymphoid cells (ILCs) have emerged as a new family of immune cells with crucial
functions in innate and adaptive immunity. ILC subsets mirror the cytokine and …

Group 3 innate lymphoid cells accumulate and exhibit disease-induced activation in the meninges in EAE

JK Hatfield, MA Brown - Cellular immunology, 2015 - Elsevier
Innate lymphoid cells are immune cells that reside in tissues that interface with the external
environment and contribute to the first line defense against pathogens. However, they also …

Cerebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation

B Bielekova, M Komori, Q Xu, DS Reich, T Wu - PloS one, 2012 - journals.plos.org
Diagnosis and management of the neuroinflammatory diseases of the central nervous
system (CNS) are hindered by the lack of reliable biomarkers of active intrathecal …

Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency

M Cols, A Rahman, PJ Maglione… - Journal of Allergy and …, 2016 - Elsevier
Background Common variable immunodeficiency (CVID) is an antibody deficiency treated
with immunoglobulin; however, patients can have noninfectious inflammatory conditions that …

Daclizumab: mechanisms of action, therapeutic efficacy, adverse events and its uncovering the potential role of innate immune system recruitment as a treatment …

SL Cohan, EB Lucassen, MC Romba, SN Linch - Biomedicines, 2019 - mdpi.com
Daclizumab (DAC) is a humanized, monoclonal antibody that blocks CD25, a critical
element of the high-affinity interleukin-2 receptor (IL-2R). DAC HYP blockade of CD25 …

Innate lymphoid cells (ILCs) as mediators of inflammation, release of cytokines and lytic molecules

NM Elemam, S Hannawi, AA Maghazachi - Toxins, 2017 - mdpi.com
Innate lymphoid cells (ILCs) are an emerging group of immune cells that provide the first line
of defense against various pathogens as well as contributing to tissue repair and …

A comprehensive review on the role of chemokines in the pathogenesis of multiple sclerosis

S Ghafouri-Fard, K Honarmand, M Taheri - Metabolic Brain Disease, 2021 - Springer
Multiple sclerosis (MS) as a chronic inflammatory disorder of the central nervous system
(CNS) is thought to be caused by the abnormal induction of immune responses …

[HTML][HTML] Therapeutic manipulation of innate lymphoid cells

LM Cobb, MR Verneris - JCI insight, 2021 - ncbi.nlm.nih.gov
Since their relatively recent discovery, innate lymphoid cells (ILCs) have been shown to be
tissue-resident lymphocytes that are critical mediators of tissue homeostasis, regeneration …

The effects of interleukin-2 on immune response regulation

RS Waters, JSA Perry, SP Han… - … and Biology: a …, 2018 - academic.oup.com
The immune system has many adaptive and dynamic components that are regulated to
ensure appropriate, precise and rapid response to a foreign pathogen. A delayed or …