[HTML][HTML] Innate lymphoid cells in tissue homeostasis and disease pathogenesis

J Kim, S Ryu, HY Kim - Molecules and cells, 2021 - Elsevier
Innate lymphoid cells (ILCs) are the most recently discovered family of innate immune cells.
ILCs can be categorized into three groups on the basis of the transcription factors that direct …

Intrathecal IgG synthesis: a resistant and valuable target for future multiple sclerosis treatments

M Bonnan - Multiple sclerosis international, 2015 - Wiley Online Library
Intrathecal IgG synthesis is a key biological feature of multiple sclerosis (MS). When
acquired early, it persists over time. A growing body of evidence suggests that intrathecal Ig …

[HTML][HTML] Natural killer cells in the central nervous system

Z Ning, Y Liu, D Guo, WJ Lin, Y Tang - Cell Communication and Signaling, 2023 - Springer
Natural killer (NK) cells are essential components of the innate lymphoid cell family that work
as both cytotoxic effectors and immune regulators. Accumulating evidence points to …

[HTML][HTML] Group 3 ILCs: peacekeepers or troublemakers? What's your gut telling you?!

E Pantazi, N Powell - Frontiers in immunology, 2019 - frontiersin.org
A complex network of interactions exists between the microbiome, the epithelium, and
immune cells that reside along the walls of the gastrointestinal tract. The intestinal immune …

The role of innate lymphoid cells in health and disease

H Mohammadi, N Sharafkandi… - Journal of cellular …, 2018 - Wiley Online Library
Innate lymphoid cells (ILCs) are kind of innate immune cells which can be divided into three
main subsets according to their cytokine release profile, transcription factors, and surface …

[HTML][HTML] Daclizumab: development, clinical trials, and practical aspects of use in multiple sclerosis

LE Baldassari, JW Rose - Neurotherapeutics, 2017 - Elsevier
Daclizumab is a humanized monoclonal antibody directed towards CD25, the alpha subunit
of the high-affinity interleukin (IL)-2 receptor. Daclizumab exerts its effects via multiple …

Considering the 'alternatives' for next-generation anti-Staphylococcus aureus vaccine development

EC O'Brien, RM McLoughlin - Trends in molecular medicine, 2019 - cell.com
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic
resistance and result in severe disease. To combat antibiotic resistance, new treatment …

Regulation of the adaptive immune system by innate lymphoid cells

MR Hepworth, GF Sonnenberg - Current opinion in immunology, 2014 - Elsevier
Highlights•Innate lymphoid cells (ILCs) are critical regulators of immune responses in
lymphoid and barrier tissues.•ILCs modulate adaptive immune cell responses indirectly …

Function of innate lymphoid cells in the immune-related disorders

T Dzopalić, B Božić-Nedeljković, V Jurišić - Human cell, 2019 - Springer
Innate lymphoid cells (ILCs) are a recently described group of innate immune cells that
mirror the characteristics of CD4+ T cell subsets. Based on their transcriptional factor and …

ILC in chronic inflammation, cancer and targeting with biologicals

C De Pasquale, S Campana, I Bonaccorsi… - Molecular Aspects of …, 2021 - Elsevier
Abstract Since their discovery, Innate Lymphoid Cells (ILC) have emerged as important
effector cells, serving multiple roles in maintaining tissue homeostasis and responding to …