Objectives The role of innate lymphoid cells (ILC), particularly helper ILC, in the
pathogenesis of multiple sclerosis (MS) is not well understood. Here, we present a …

Modulation of the immune system has been widely targeted for the treatment of several
immune-related diseases, such as autoimmune disorders and cancer, due to its crucial role …

Multiple sclerosis (MS) is a chronic inflammatory disease of the CNS, and one of the most
common causes of disability in young adults. Over the last decade, new disease‐modifying …

Innate lymphoid cells (ILCs) are a newly classified family of immune cells of the lymphoid
lineage. While they could be found in both lymphoid organs and non-lymphoid tissues, ILCs …

Abstract Background and Objective Daclizumab is a humanized monoclonal antibody that
blocks the α-subunit of the interleukin-2 receptor with demonstrated benefits in the treatment …

Background: Inflammatory cytokines produced by cells of the immune system are believed to
play a central role in the pathogenesis of multiple sclerosis (MS). Innate lymphoid cells …

Immune reconstitution therapies (IRTs) are a type of short course procedure or
pharmaceutical agent within the MS pharmacopeia. They emanate from oncology and …

Daclizumab is a monoclonal antibody that reduces inflammation in multiple sclerosis (MS).
Through a retrospective analysis, our objective was to determine whether daclizumab …

The most recently recognized types of immune cells, the innate lymphoid cells (ILCs), have
been sub-divided according to respective distinct expression profiles of regulatory factors …

Autoinflammatory attacks in familial Mediterranean fever (FMF) are accompanied by
elevated levels of interleukin-6 (IL-6), and are controllable by IL-1-targeting drugs. In …