There are numerous investigated factors that limit brain cancer treatment efficacy such as
ability of prescribed therapy to cross the blood-brain barrier (BBB), tumor specific delivery of …

The expression, localization, and function of connexins, the protein subunits that comprise
gap junctions, are often altered in cancer. In addition to cell–cell coupling through gap …

Head and neck squamous cell carcinoma (HNSCC) is often being diagnosed at an
advanced stage, conferring a poor prognosis. The probability of local tumor control after …

The 'cancer stem cell'hypothesis has pointed to a specific target for new cancer therapies.
The hypothesis is based on the observation that only the 'cancer stem cell'among the other …

If occupational tumors are excluded, cancer causes are largely unknown. Therefore, it
appeared useful to work out a theory explaining the complexity of this disease. More than …

Growing evidence suggests dietary antioxidants reduce the risk of several cancers. Grape
seeds extracts (GSE) are a rich source of polyphenols known to have antioxidant …

Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore
are responsible for poor survival. Molecular signatures of BCSCs from primary cancers …

Gap junction proteins are expressed in cancer stem cells and non-stem cancer cells of many
tumors. As the morphology and assembly of gap junction channels are crucial for their …

Simple Summary Connexins are proteins which comprise gap junctions in cells. These
junctions can directly connect neighboring cells and the cell interior with the extracellular …

The development of many forms of intercellular communication was essential for the
evolution of multicellular organisms. The organization of cells into tissues and organs and …