Inflammatory demyelinating diseases (IDDs) are among the main causes of inflammatory
and neurodegenerative injury of the central nervous system (CNS) in young adult patients …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by destruction of the myelin sheath structure. The loss of myelin leads …

Rationale: Myocardial infarction (MI) is one of the most dangerous adverse cardiovascular
events. Our previous study found that lysophosphatidic acid (LPA) is increased in human …

Glaucoma is a leading cause of permanent blindness worldwide and is characterized by
neurodegeneration linked to progressive retinal ganglion cell (RGC) death, axonal damage …

Although the understanding of secondary progressive multiple sclerosis (SPMS) is evolving,
early detection of relapse-independent progression remains difficult. This is further …

Disorders of the central nervous system (CNS), such as multiple sclerosis (MS) represent a
great emotional, financial and social burden. Despite intense efforts, great unmet medical …

Glaucoma is a complex neurodegenerative disease characterized by optic nerve damage
and apoptotic retinal ganglion cell (RGC) death, and is the leading cause of irreversible …

Theranostic imaging methods could greatly enhance our understanding of the distribution of
CNS-acting drugs in individual patients. Fluorine-19 magnetic resonance imaging (19 F …

Over the past few decades, extensive research has shed light on immune alterations and the
significance of dysfunctional biological barriers in psychiatric disorders. The leaky gut …

Background Observational studies have suggested an association between multiple
sclerosis (MS) and cortical structure, but the results have been inconsistent. Objective We …