The efficacy of standard antidepressants is limited for many patients with mood disorders
such as major depressive disorder (MDD) and bipolar depression, underscoring the urgent …

The pathophysiology of major depressive disorder (MDD) is thought to result from impaired
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …

Objective: Postpartum depression (PPD) is a common perinatal complication with adverse
maternal and infant outcomes. This study investigated the efficacy and safety of zuranolone …

Importance Postpartum depression (PPD) is one of the most common medical complications
during and after pregnancy, negatively affecting both mother and child. Objective To …

Positive allosteric modulators of γ-aminobutyric acid-A (GABA A) receptors or GABAkines
have been widely used medicines for over 70 years for anxiety, epilepsy, sleep, and other …

Premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) are common
disorders of the luteal phase of the menstrual cycle and are characterized by moderate to …

Whether a major depressive episode occurring in the postpartum period (ie, postpartum
depression [PPD]) is sufficiently distinct from major depressive episodes occurring at other …

Objective: To review the safety and efficacy of brexanolone for the treatment of moderate to
severe postpartum depression (PPD). Data Sources: A literature search through PubMed …

This article describes the critical role of neurosteroids in postpartum depression (PPD) and
outlines the landmark pharmacological journey of brexanolone as a first-in-class …

Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …