Structural characterization and biological activity of a new metal complexes based of Schiff base

OA El-Gammal, FS Mohamed, GN Rezk… - Journal of Molecular …, 2021 - Elsevier
Metal complexes of Co (II), Ni (II) and Cu (II) complexes (1–3) with a new Schiff base (HL)
have been prepared and characterized by elemental analyses IR, UV–Visible, magnetic …

Design, synthesis, in vitro and in silico investigation of aldose reductase inhibitory effects of new thiazole-based compounds

B Sever, MD Altıntop, Y Demir, GA Çiftçi, Ş Beydemir… - Bioorganic …, 2020 - Elsevier
Aldose reductase (AR) catalyzes the NADPH-dependent reduction of glucose to sorbitol in
the polyol pathway, which plays an important role in the development of diabetic …

Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening …

RA Kardile, AP Sarkate, DK Lokwani, SV Tiwari… - European Journal of …, 2023 - Elsevier
Here in, we report the design, synthesis and in vitro anticancer activity of a novel series of 24
quinoline analogues of substituted amide and sulphonamide derivatives. The anticancer …

[HTML][HTML] Synthesis of new series of quinoline derivatives with insecticidal effects on larval vectors of malaria and dengue diseases

K Murugan, C Panneerselvam, J Subramaniam… - Scientific reports, 2022 - nature.com
Mosquito borne diseases are on the rise because of their fast spread worldwide and the lack
of effective treatments. Here we are focusing on the development of a novel anti-malarial …

[PDF][PDF] Synthesis, characterization, DFT calculations and biological activity of new Schiff base complexes

FM Alkhatib, HM Alsulami - Heliyon, 2023 - cell.com
Schiff bases ligand (HL) was produced by condensing 4-aminobenzohydrazide with N-(4-
chlorophenyl)-2-(4-formylphenoxy) acetamide. Cobalt (II), nickel (II), and copper (II) acetate …

Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition

MS Nafie, SM Kishk, S Mahgoub… - Chemical Biology & …, 2022 - Wiley Online Library
Quinoline‐based thiazolidinone heterocycles exhibited potent activity in the field of cancer
therapy. Hence, ten quinoline‐based thiazolidinone derivatives were evaluated for their …

Structural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteres

JB Araškov, M Nikolić, S Armaković… - Journal of molecular …, 2021 - Elsevier
To evaluate the impact of chalcogen atom type, we performed a comparative study of
antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based …

Catalyst-Free Synthesis of 2-Anilinoquinolines and 3-Hydroxyquinolines via Three-Component Reaction of Quinoline N-Oxides, Aryldiazonium Salts, and Acetonitrile

AK Dhiman, D Chandra, R Kumar… - The Journal of Organic …, 2019 - ACS Publications
A rapid microwave-assisted, catalyst-free, three-component synthesis of various 2-
anilinoquinolines from quinoline N-oxides and aryldiazonium salts in acetonitrile under …

A new series of thiazole‐hydrazone hybrids for Akt‐targeted therapy of non‐small cell lung cancer

T Orujova, A Ece, G Akalın Çiftçi… - Drug Development …, 2023 - Wiley Online Library
In an attempt to identify potent antitumor agents for the fight against non‐small cell lung
cancer, new thiazolyl hydrazones (2a–n) were synthesized and examined for their in vitro …

[HTML][HTML] Synthesis, structure, chemical stability, and in vitro cytotoxic properties of novel quinoline-3-carbaldehyde hydrazones bearing a 1, 2, 4-triazole or …

M Korcz, F Sączewski, PJ Bednarski, A Kornicka - Molecules, 2018 - mdpi.com
A small library of novel quinoline-3-carbaldehyde hydrazones (Series 1), acylhydrazones
(Series 2), and arylsulfonylhydrazones (Series 3) bearing either a 1, 2, 4-triazole or …