Uterine spiral arteries play a vital role in supplying nutrients to the placenta and fetus, and
for this purpose they are remodelled into highly dilated vessels by the action of invading …

Citation Sharp AN, Heazell AEP, Crocker IP, Mor G. Placental apoptosis in health and
disease. Am J Reprod Immunol 2010; 64: 159–169 Apoptosis, programmed cell death, is an …

Objective: We sought to determine morphologically when the maternal uterine circulation to
the human placenta is established. Study Design: We performed a histologic review of 12 …

The placenta is a gender-specific transitory organ with the sole purpose of enabling the
growth and development of the fetus. It mediates the efficient transfer and exchange of …

STUDY QUESTION Does the use of a vascular contrast agent facilitate earlier detection of
maternal flow to the placental intervillous space (IVS) in the first trimester of pregnancy …

Our understanding of how cells communicate has undergone a paradigm shift since the
recent recognition of the role of exosomes in intercellular signaling. In this study, we …

STUDY QUESTION How does trophoblast plugging impact utero-placental
haemodynamics? SUMMARY ANSWER Physiological trophoblast plug structures are dense …

In the first trimester of human pregnancy villous cytotrophoblasts are able to differentiate to
form either the overlying syncytiotrophoblast layer or, in anchoring villi, extravillous …

In the first 20 weeks of pregnancy a number of important changes take place in the maternal
uterine vasculature. Vascular endothelial and smooth muscle cells are lost from the spiral …

The phenomenon of implantation anchors the embryo into the uterine wall and produces a
hemochorial placenta that maintains the pregnancy and fetal growth. Implantation and …