Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now
threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae …

Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

The management of infections due to Klebsiella pneumoniae has been complicated by the
emergence of antimicrobial resistance, especially to carbapenems. Resistance to …

Carbapenem resistant Enterobacteriaceae (CRE) pose an urgent risk to global human
health. CRE that are non-susceptible to all commercially available antibiotics threaten to …

Klebsiella pneumoniae, one of the most important nosocomial pathogens, is becoming a
major problem in health care because of its resistance to multiple antibiotics, including …

Carbapenems are the last resort antimicrobials for the treatment of extended spectrum β-
lactamases (ESBLs) producing Enterobacteriaceae. Emergence of carbapenems resistant …

The in vitro activities of ceftazidime-avibactam and comparators against 9,149 isolates of
Enterobacteriaceae and 2,038 isolates of Pseudomonas aeruginosa collected by 42 …

Carbapenem-hydrolysing enzymes belonging to the OXA-48-like group are encoded by bla
OXA-48-like alleles and are abundant among Enterobacterales in the Netherlands …

Carbapenemases have become a significant mechanism for broad-spectrum β-lactam
resistance in Enterobacteriaceae and other Gram-negative bacteria such as Pseudomonas …