[HTML][HTML] The pharmacological and biological importance of EZH2 signaling in lung cancer

M Entezari, A Taheriazam, MDA Paskeh… - Biomedicine & …, 2023 - Elsevier
Up to 18% of cancer-related deaths worldwide are attributed to lung tumor and global
burden of this type of cancer is ascending. Different factors are responsible for development …

[HTML][HTML] Current Advances and Future Strategies for BCL-2 Inhibitors: Potent Weapons against Cancers

J Xu, X Dong, DCS Huang, P Xu, Q Zhao, B Chen - Cancers, 2023 - mdpi.com
Simple Summary The development of BCL-2 inhibitors as a pivotal approach in cancer
treatment lies in their ability to effectively trigger apoptosis in tumor cells. Venetoclax, a …

[HTML][HTML] Design of gefitinib-loaded PLGA microspheres via microfluidics for lung cancer

R Huang, H Zhang, L Lv, Y Zhang, J Li, H Wang… - Materials & Design, 2023 - Elsevier
Lung cancer is one of the most prevalent tumors with rapid progression and poor prognosis,
which badly affects human physical and mental health. Although traditional anti-cancer …

[HTML][HTML] Deciphering the effects and mechanisms of Yi-Fei-San-Jie-pill on non-small cell lung cancer with integrating network target analysis and experimental …

H Yang, Q Guo, J Wu, L Zhong, L Sun, W Liu… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung cancer (NSCLC), which accounts for 85% of lung cancer cases, calls for
better therapy. Yi-Fei-San-Jie-pill (YFSJ), a well-applicated traditional Chinese medicine …

The underlying mechanism involved in gefitinib resistance and corresponding experiment validation in lung cancer

P Song, J Zhou, K Wu, W Wang… - Mediators of Inflammation, 2023 - Wiley Online Library
Background. Gefitinib resistance remains a major problem in the treatment of lung cancer.
However, the underlying mechanisms involved in gefitinib resistance are largely unclear …

Caffeic acid phenethyl ester surmounts acquired resistance of AZD9291 in non‐small cell lung cancer cells

Y Twum, K Marshall, W Gao - BioFactors, 2023 - Wiley Online Library
Epithelial growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) are the first‐line
therapy for EGFR mutated non‐small cell lung cancer (NSCLC); however, resistance rapidly …

Proteome derangement in malignant epithelial cells and its stroma following exposure to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

K Marshall, Y Twum, W Gao - Archives of toxicology, 2023 - Springer
Discovering novel changes in the proteome of malignant lung epithelial cells and/or the
tumor-microenvironment is paramount for diagnostic, prognostic, and/or therapy …