Several strands of evidence indicate the presence of marked similarities between human
brain and testis. Understanding these similarities and their implications has become a topic …

Abstract Calcium ions (Ca 2+) are involved in nearly every aspect of cellular life. They are
one of the most abundant elements in mammals and play a vital role in physiological and …

Purification of membrane proteins for biochemical and structural studies is commonly
achieved by recombinant overexpression in heterologous cell lines. However, many …

Simple Summary Electrolyte balance is very significant, ensures homeostasis of the
organism, maintains reactions, nerve conduction, and proper polarity of cell membranes …

BACKGROUND The high rates of unintended pregnancy and the ever-growing world
population impose health, economic, social, and environmental threats to countries …

Spermatogenesis is a cell differentiation process that ensures the production of fertilizing
sperm, which ultimately fuse with an egg to form a zygote. Normal spermatogenesis relies …

Introduction Cisplatin, a commonly used anticancer compound, exhibits severe off-target
organ toxicity. Due to its wide application in cancer treatment, the reduction of its damage to …

To fertilize an oocyte, sperm must undergo several biochemical and functional changes
known as capacitation. A key event in capacitation is calcium influx through the cation …

In mammals, sperm fertilization potential relies on efficient progression within the female
genital tract to reach and fertilize the oocyte. This fundamental property is supported by the …

Alkalinization of sperm cytosol is essential for plasma membrane hyperpolarization,
hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals …