Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …
Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments
S Liu, Z Deng, K Chen, S Jian… - Molecular …, 2022 - spandidos-publications.com
Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …
Injective mesenchymal stem cell-based treatments for knee osteoarthritis: from mechanisms of action to current clinical evidences
Purpose Osteoarthritis (OA) represents a relevant social and economic burden worldwide.“
Mesenchymal stem cells” or, as recently proposed,“medicinal signaling cells”(MSCs) have …
Mesenchymal stem cells” or, as recently proposed,“medicinal signaling cells”(MSCs) have …
Pathophysiological perspective of osteoarthritis
Osteoarthritis (OA) is the most well-known degenerative disease among the geriatric and is
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
a main cause of significant disability in daily living. It has a multifactorial etiology and is …
[HTML][HTML] NLRP3 as a potentially novel biomarker for the management of osteoarthritis
MJ McAllister, M Chemaly, AJ Eakin, DS Gibson… - Osteoarthritis and …, 2018 - Elsevier
Osteoarthritis (OA) was previously thought of as 'wear and tear'as humans age, however
there is increasing evidence to support an inflammatory theory. The nucleotide-binding and …
there is increasing evidence to support an inflammatory theory. The nucleotide-binding and …
Beyond mechanical loading: The metabolic contribution of obesity in osteoarthritis unveils novel therapeutic targets
BH Sobieh, HO El-Mesallamy, DH Kassem - Heliyon, 2023 - cell.com
Osteoarthritis (OA) is a prevalent progressive disease that frequently coexists with obesity.
For several decades, OA was thought to be the result of ageing and mechanical stress on …
For several decades, OA was thought to be the result of ageing and mechanical stress on …
The effect of intra-articular injection of autologous microfragmented fat tissue on proteoglycan synthesis in patients with knee osteoarthritis
Osteoarthritis (OA) is one of the leading musculoskeletal disorders in the adult population. It
is associated with cartilage damage triggered by the deterioration of the extracellular matrix …
is associated with cartilage damage triggered by the deterioration of the extracellular matrix …
Past, present, and future of cartilage restoration: from localized defect to arthritis
DH Lee, SJ Kim, SA Kim, G Ju - Knee Surgery & Related Research, 2022 - Springer
Background Osteoarthritis, one of the most common joint diseases, is characterized by the
loss of joint function due to articular cartilage destruction. Herein, we review current and …
loss of joint function due to articular cartilage destruction. Herein, we review current and …
Identification and development of a novel 5-gene diagnostic model based on immune infiltration analysis of osteoarthritis
Background Osteoarthritis (OA), which is due to the progressive loss and degeneration of
articular cartilage, is the leading cause of disability worldwide. Therefore, it is of great …
articular cartilage, is the leading cause of disability worldwide. Therefore, it is of great …
Cartilage acidic protein 1 in plasma associates with prevalent osteoarthritis and predicts future risk as well as progression to joint replacements: results from the UK …
U Styrkarsdottir, SH Lund, G Thorleifsson… - Arthritis & …, 2023 - Wiley Online Library
Objective The level of cartilage acidic protein 1 (CRTAC1) in plasma was recently
discovered to be associated with osteoarthritis (OA) risk and progression to joint …
discovered to be associated with osteoarthritis (OA) risk and progression to joint …