Despite increased pulsatile stress, thrombotic rather than hemorrhagic events represent a
major complication of hypertension. The pathophysiology of thrombosis in hypertension …

The renal vasculature plays a major role in the regulation of renal blood flow and the ability
of the kidney to control the plasma volume and blood pressure. Renal vascular dysfunction …

Sex hormones contribute to sex differences in blood pressure. Inappropriate activation of the
renin-angiotensin system is involved in vascular dysfunction and hypertension. This study …

Introduction: Hypertension is a leading cause of cardiovascular disease and chronic kidney
disease, resulting in premature death and disability. The Renin-Angiotensin-Aldosterone …

Recent studies show that angiotensin II stimulates the nitric oxide system via angiotensin II
type 1 and angiotensin II type 2 receptors, whereas receptors exert different effects on renal …

Objective The present study was designed to test the hypothesis that inflammation is
involved in the end-organ damage (EOD) induced by sinoaortic denervation (SAD) in rats …

Resistance changes of the afferent and efferent arterioles determine blood flow and filtration
rate in the kidney. The tone of both vessels results from the influence of nerves and humoral …

It is unclear whether single and combined pharmacologic inhibition of the renin‐angiotensin‐
aldosterone system have similar effects on endothelial function and blood pressure (BP) …

Aims Previous studies suggested that androgens augmented renal vascular responses to
angiotensin II (Ang II). The protein kinase C (PKC)-CPI-17 pathway is involved in vascular …

Aims: To examine whether the blood pressure (BP) profiles of lumiracoxib and high‐dose
ibuprofen differed in patients treated with different classes of antihypertensive medications …