Advances in 3D printing for tissue engineering

A Zaszczyńska, M Moczulska-Heljak, A Gradys… - Materials, 2021 - mdpi.com
Tissue engineering (TE) scaffolds have enormous significance for the possibility of
regeneration of complex tissue structures or even whole organs. Three-dimensional (3D) …

[HTML][HTML] 3D bioprinting with live cells

A Persaud, A Maus, L Strait, D Zhu - Engineered Regeneration, 2022 - Elsevier
In recent years, the shortage of available organs for transplant patients has grown
exponentially across the globe. Consequently, the healthcare industry is in dire need of …

Advances in 3D bioprinting for cancer biology and precision medicine: From matrix design to application

MS Jung, S Ghamrawi, EY Du… - Advanced …, 2022 - Wiley Online Library
The tumor microenvironment is highly complex owing to its heterogeneous composition and
dynamic nature. This makes tumors difficult to replicate using traditional 2D cell culture …

[HTML][HTML] Commercialization and regulation of regenerative medicine products: Promises, advances and challenges

N Beheshtizadeh, M Gharibshahian… - Biomedicine & …, 2022 - Elsevier
The ultimate goal of regenerative medicine is to repair, regenerate, or reconstruct functional
loss in failed tissues and/or organs. Although regenerative medicine is a relatively new field …

3D bioprinting complex models of cancer

R Sharma, MR Perez, VA da Silva, J Thomsen… - Biomaterials …, 2023 - pubs.rsc.org
Cancer is characterized by the uncontrolled division of cells, resulting in the formation of
tumors. The tumor microenvironment (TME) consists of a variety of cell types present within a …

Assessment of synthesized chitosan/halloysite nanocarrier modified by carbon nanotube for pH-sensitive delivery of curcumin to cancerous media

A Farokh, M Pourmadadi, H Rashedi, F Yazdian… - International Journal of …, 2023 - Elsevier
Constructing a system to carry medicine for more effective remedy of cancer has been a
leading challenge, as the number of cancer cases continues to increase. In this present …

Human liver cancer organoids: Biological applications, current challenges, and prospects in hepatoma therapy

L Chen, X Wei, D Gu, Y Xu, H Zhou - Cancer Letters, 2023 - Elsevier
Liver cancer and disease are among the most socially challenging global health concerns.
Although organ transplantation, surgical resection and anticancer drugs are the main …

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

LF Lorenzo-Martín, T Hübscher, AD Bowler… - Nature, 2024 - nature.com
Three-dimensional organoid culture technologies have revolutionized cancer research by
allowing for more realistic and scalable reproductions of both tumour and …

[PDF][PDF] Functional genomics and the future of iPSCs in disease modeling

IR Brooks, CM Garrone, C Kerins, CS Kiar, S Syntaka… - Stem cell reports, 2022 - cell.com
Induced pluripotent stem cells (iPSCs) are valuable in disease modeling because of their
potential to expand and differentiate into virtually any cell type and recapitulate key aspects …

Mechanical studies of the third dimension in cancer: From 2D to 3D model

F Paradiso, S Serpelloni, LW Francis… - International Journal of …, 2021 - mdpi.com
From the development of self-aggregating, scaffold-free multicellular spheroids to the
inclusion of scaffold systems, 3D models have progressively increased in complexity to …