Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

GB Kubat, E Bouhamida, O Ulger, I Turkel, G Pedriali… - Mitochondrion, 2023 - Elsevier
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Role of growth differentiation factor 15 in cancer cachexia

T Ling, J Zhang, F Ding, L Ma - Oncology Letters, 2023 - spandidos-publications.com
Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth
factor‑β family, is a stress‑induced cytokine. Under normal circumstances, the expression of …

Mechanisms of Ovarian Cancer-Associated Cachexia

CS Callaway, LM Mouchantat, BG Bitler… - Endocrinology, 2024 - academic.oup.com
Cancer-associated cachexia occurs in 50% to 80% of cancer patients and is responsible for
20% to 30% of cancer-related deaths. Cachexia limits survival and treatment outcomes, and …

Is MG53 a potential therapeutic target for cancer?

Y Du, T Li, M Yi - Frontiers in endocrinology, 2023 - frontiersin.org
Cancer treatment still encounters challenges, such as side effects and drug resistance. The
tripartite-motif (TRIM) protein family is widely involved in regulation of the occurrence …

Maintenance of the branched-chain amino acid transporter LAT1 counteracts myotube atrophy following chemotherapy

S Mora, OAJ Adegoke - American Journal of Physiology …, 2024 - journals.physiology.org
Prevention/management of cachexia remains a critical issue in muscle wasting conditions.
The branched-chain amino acids (BCAA) have anabolic properties in skeletal muscle, but …

Effect of combined Kinesiotaping and resistive exercise on muscle strength and quality of life in breast cancer survivors: a randomized clinical trial

AM Ramadan, AM ElDeeb, AA Ramadan… - Journal of the Egyptian …, 2024 - Springer
Background Breast cancer (BC) and its treatment affect women's tissue architecture and
physiology, which leads to impaired muscle strength and joint dysfunction, affecting quality …

Sarcopenic Obesity and Outcomes for Patients With Cancer

C Liu, T Liu, L Deng, Q Zhang, M Song, J Shi… - JAMA Network …, 2024 - jamanetwork.com
Importance The European Society for Clinical Nutrition and Metabolism (ESPEN) and the
European Association for the Study of Obesity (EASO) have recently proposed a consensus …

The Impact of Non-bone Metastatic Cancer on Musculoskeletal Health

F Galiana-Melendez, JR Huot - Current Osteoporosis Reports, 2024 - Springer
The Impact of Non-bone Metastatic Cancer on Musculoskeletal Health | Current Osteoporosis
Reports Skip to main content SpringerLink Account Menu Find a journal Publish with us Track …

The association of body composition phenotypes before chemotherapy with epithelial ovarian cancer mortality

EW Davis, K Attwood, J Prunier… - JNCI: Journal of the …, 2024 - academic.oup.com
Background The association of body composition with epithelial ovarian carcinoma (EOC)
mortality is poorly understood. To date, evidence suggests high adiposity associates with …

[HTML][HTML] Toward a holistic understanding of cancer cachexia: application of the human response to illness model

SE McClement - Asia-Pacific Journal of Oncology Nursing, 2023 - Elsevier
Cachexia is a commonly presenting multidimensional syndrome in individuals living with
advanced cancer. Given its prevalence of between 50% and 80%, nurses are going to …