[HTML][HTML] Therapeutic Effects of Mesenchymal Stromal Cells Require Mitochondrial Transfer and Quality Control
AN Mukkala, M Jerkic, Z Khan, K Szaszi… - International Journal of …, 2023 - mdpi.com
Due to their beneficial effects in an array of diseases, Mesenchymal Stromal Cells (MSCs)
have been the focus of intense preclinical research and clinical implementation for decades …
have been the focus of intense preclinical research and clinical implementation for decades …
Mechanisms of Pulmonary Vasculopathy in Acute and Long-Term COVID-19: A Review
M Riou, F Coste, A Meyer, I Enache, S Talha… - International Journal of …, 2024 - mdpi.com
Despite the end of the pandemic, coronavirus disease 2019 (COVID-19) remains a major
public health concern. The first waves of the virus led to a better understanding of its …
public health concern. The first waves of the virus led to a better understanding of its …
[HTML][HTML] Hypoxia-induced pulmonary hypertension in adults and newborns: implications for drug development
Chronic hypoxia-induced pulmonary hypertension (CHPH) presents a complex challenge,
characterized by escalating pulmonary vascular resistance and remodeling, threatening …
characterized by escalating pulmonary vascular resistance and remodeling, threatening …
[HTML][HTML] Implication of Rac1 GTPase in molecular and cellular mitochondrial functions
C Bailly, C Degand, W Laine, V Sauzeau, J Kluza - Life Sciences, 2024 - Elsevier
Rac1 is a member of the Rho GTPase family which plays major roles in cell mobility, polarity
and migration, as a fundamental regulator of actin cytoskeleton. Signal transduction by Rac1 …
and migration, as a fundamental regulator of actin cytoskeleton. Signal transduction by Rac1 …
[HTML][HTML] Exosomes enriched by miR-429-3p derived from ITGB1 modified Telocytes alleviates hypoxia-induced pulmonary arterial hypertension through regulating …
R Qi, Y Zhang, F Yan - Cell Biology and Toxicology, 2024 - Springer
Background Recent studies have emphasized the critical role of Telocytes (TCs)-derived
exosomes in organ tissue injury and repair. Our previous research showed a significant …
exosomes in organ tissue injury and repair. Our previous research showed a significant …
[HTML][HTML] How Nitric Oxide Hindered the Search for Hemoglobin-Based Oxygen Carriers as Human Blood Substitutes
M Samaja, A Malavalli, KD Vandegriff - International Journal of Molecular …, 2023 - mdpi.com
The search for a clinically affordable substitute of human blood for transfusion is still an
unmet need of modern society. More than 50 years of research on acellular hemoglobin …
unmet need of modern society. More than 50 years of research on acellular hemoglobin …
Role of exercise in pulmonary hypertension: Evidence from bench to bedside
Background: Pulmonary hypertension (PH) is a debilitating condition characterized by
elevated pulmonary arterial pressure and progressive vascular remodeling, leading to …
elevated pulmonary arterial pressure and progressive vascular remodeling, leading to …
Mitochondrial dysfunction drives the pathogenesis of pulmonary arterial hypertension: insights from a multi-omics investigation
X Zhang, J Li, M Fu, X Geng, J Hu, K Tang, P Chen… - 2023 - researchsquare.com
Background Pulmonary arterial hypertension (PAH) is a progressive disorder that can lead
to right ventricular failure and severe consequences. Despite extensive efforts, limited …
to right ventricular failure and severe consequences. Despite extensive efforts, limited …
[PDF][PDF] Caracterización del modelo murino Yme1l knockout en el endotelio desde el punto de vista de la Hipertensión Pulmonar
B García-León, Y Sierra-Palomares, D Lobato-Alonso… - biociencias.es
Resumen La Hipertensión Arterial Pulmonar (HAP) es una enfermedad rara con alta
mortalidad y morbilidad. Sus principales características son el remodelado vascular y la …
mortalidad y morbilidad. Sus principales características son el remodelado vascular y la …